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A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled
Triggering final oocyte maturation with kisspeptin is a novel therapeutic option to enable the use of fresh embryo transfer even in the woman at high risk of OHSS.
Do Sperm Really Compete and Do Eggs Ever Have a Choice? Adult Distribution and Gamete Mixing Influence Sexual Selection, Sexual Conflict, and the Evol
Field experiments and a simple heuristic model examining the degree of sperm mixing for the sea urchin Strongylocentrotus franciscanus indicate that degree of competitive fertilization depends on density and distribution of competing males and that the nature of this competition influences whether males with high- or low-affinity gamete recognition protein genotypes have higher reproductive success.
Chromatin Protamination and Catsper Expression in Spermatozoa Predict Clinical Outcomes after Assisted Reproduction Programs
CMA3 positivity and CATSPER expression significantly predicted the attainment of good quality embryos with an OR of 6.6 and 14.3 respectively, whereas AB staining was correlated with fertilization rate. In the subgroup of couples with women ≤:35 years, CATSPER also predicted achievement of clinical pregnancy (OR := :4.4). Including CMA3, CATSPER and other parameters affecting ART outcomes (female age, female factor and number of MI
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios
In conclusion, there seems to be a consensus that increased sperm DFI is associated with a lower chance of pregnancy with natural pregnancy, IUI and IVF, but not ICSI. Despite the rapid development of artificial reproductive methods, repeated implantation failure, inadequate response to surgical treatment of varicocele, and the inadequacy of standard laboratory tests/semen analysis to demonstrate the cause of idiopathic male infertility prompted
Infertility, recurrent pregnancy loss and sperm DNA fragmentation, have we found the missing link?
Moreover, SDF was found to be inversely correlated with the success of fertility treatments including live birth rates (28). Despite this well-established observation, SDF is not widely accepted as part of the evaluation of infertility or RPL. Possible reasons for the under-use of SDF are lack of information, expensive required equipment, but most importantly, the common belief that SDF is untreatable and therefore is irrelevant.
Sperm DNA fragmentation testing: a cross sectional survey on current practices of fertility specialists
SDF testing is utilized in the evaluation of infertility patients by a majority of fertility specialists under specific clinical scenarios. Shortcomings, such as the presence of several SDF testing methods with different cut-off values and the test charges were some of the reasons hampering the routine use of SDF in the evaluation of infertile men.
The Society for Translational Medicine: clinical practice guidelines for sperm DNA fragmentation testing in male infertility
This clinical practice guideline provides recommendations of clinical utility of the test supported by evidence. It is intended to serve as a reference for fertility specialists in identifying the circumstances in which SDF testing should be of greatest clinical value. SDF testing is recommended in patients with clinical varicocele and borderline to normal semen parameters as it can better select varicocelectomy candidates.
CO2 Incubators and Your Media Prep Routine [Safe Sens Distribution]
The incubator is widely considered the most critical piece of equipment in the ART laboratory. The type of incubator, its age, and its physical location all affect performance. These changes to performance will affect your embryo culture conditions, and can be reflected in pH trend analysis.
Fragile X: Eastbury family reach settlement with IVF clinic over boys inheriting gene
The parents of two boys who inherited an intellectual disability say they can move on with their lives now they have reached a settlement with a Sydney IVF clinic. An agreement was reached with Genea, formerly known as Sydney IVF, after Leighee Eastbury filed a lawsuit claiming they failed to identify she was a carrier of the Fragile X syndrome.
Rival sperm and choosy eggs: When sperm compete , eggs have a choice [Sea urchin].
The delicately mannered dance between discerning eggs and vying sperm is more complicated than scientists once believed, and it may hold secrets about the evolution of new species.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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