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Association between ambient air pollution and pregnancy rate in women who underwent IVF
This study provided evidence of an association between increased ambient concentrations of PM10, NO2 and CO and reduced probabilities for achieving intrauterine pregnancy using multiple IVF cycle data. Specifically, our results indicated that lower intrauterine pregnancy rates in IVF cycles may be linked to ambient air pollution during COS and the post-transfer period.
Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting
This proceedings report presents the outcomes from an international Expert Meeting to establish a consensus on the recommended technical and operational requirements for air quality within modern assisted reproduction technology (ART) laboratories. These consensus points should be considered as aspirational benchmarks for existing ART laboratories, and as guidelines for the construction of new ART laboratories.
Although Day 7 blastocysts make up only 5% of useable blastocysts, those which are suitable for cryopreservation or biopsy are clinically significant. Overall, culturing embryos an additional day increases the number of useable embryos per IVF cycle and provides further opportunity for pregnancy for patients, especially those who have only a few or low-quality blastocysts.
Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental System
Our results demonstrate evidence of PGE2-mediated effects of acetaminophen and ibuprofen on GC/NTera2 cells, which raises concerns about analgesic use during human pregnancy that warrant further investigation.
Painkillers in pregnancy may affect baby's future fertility
Taking painkillers during pregnancy could affect the fertility of the unborn child in later life, research suggests. Scientists looked at the effects of paracetamol (acetaminophen) and ibuprofen on samples of human fetal testes and ovaries. Their findings add to a growing body of evidence that the medicines should be used with caution during pregnancy.
Can ambient air pollution influence the chance and outcome of pregnancy?
Summary
The authors reported that exposure to PM,CO and NO2 (but not SO2 and O3) after embryo transfer decreased the chance of pregnancy and the outcome of pregnancy
Comment
In this South Korean article, the authors looked at averaged air pollutant concentration PM (particulate matter), CO, NO2, SO2 and O3 from general published environmental data and related the level of pollution to pregnancy outcomes during the whole IVF treatment cycle. They reported that high exposure of both PM, CO and NO2 during the post embryo transfer period (implantation period) decreased both the chance of pregnancy and the miscarriage rate.| While they acknowledged that other factors such as smoking may be contributing effects, the power of the study lay in the 6621 cycles from 4581 patients between 2006 and 2014. It seems the data related only to IVF cycles and it would be interesting the results for a similar study from FET cycles. It was assumed most of the pollution arose from vehicle traffic.|This impressive paper demonstrated that the environment in which couples are trying to conceive may directly influence their chance of pregnancy and the likelihood the pregnancy will proceed to term. Perhaps clinics working in pristine climates (with little traffic) may like to use this information to promote their clinics but the paper does imply that the environment outside the laboratory has an influence on their success rates. There is a lot of information on the sources of VOC toxicity from laboratory processes on pregnancy and reports of pregnancy reductions during building renovations including car park resurfacing but this paper extends this concept to exposure after the embryos have been transferred. Should clinics explain this to couples where treatment is in a highly polluted city and maybe have a holiday after the transfer? If the clinic is in a highly polluted city, then monthly KPI data may vary during the seasons when the pollution levels may change.|
IVFLabOnline - Recent Enteries to IVFLabOnlines product listings.see IVFLabonline
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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