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Preimplantation embryos sex ratios in couples with four or more children of same sex, what should be expected from a preimplantation genetic diagnosis
For couples desiring a boy, IVF cycles achieved a higher ratio of the desired embryonal sex compared to ICSI (52% vs 18.7%, p := :.03). For couples desiring a girl, ICSI cycles had a higher percentage of the desired embryonal sex compared to IVF cycles (38% vs 23%). Moreover, 29.7% of ICSI and 40% of IVF embryos achieved the desired sex. In conclusion, PGD for sex selection results in a relatively low percentage (35%) of embryos demons
Adverse effects of paternal obesity on the motile spermatozoa quality
Our results showed that the motile sperm-enriched fraction from obese men exhibited higher levels of retained histones (p<0.001), elevated percentage of altered chromatin integrity (p<0.001), and decreased contents of 5-hmC (p<0.001), and 5-mC (p<0.05) levels as compared to that from lean men. Importantly, there were no statistically significant correlations between these molecular parameters and the percentages of morphologically normal motile s
Increased body mass index associated with increased preterm delivery in frozen embryo transfers
What do the results of this study add? Underweight, overweight and obesity do not significantly contribute to live birth outcomes. Maternal BMI was a significant predictor of PTD, with obesity most significantly at risk of PTD.
Marijuana smoking and markers of testicular function among men from a fertility centre
These findings are not consistent with a deleterious effect of marijuana on testicular function. Whether these findings are reflective of the previously described role of the endocannabinoid system in spermatogenesis or a spurious association requires confirmation in further studies.
Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development
In postmeiotic round spermatids, genomic compartmentalization increases and gives rise to the strong compartmentalization seen in mature sperm. The X chromosome lacks domain organization during meiotic sex-chromosome inactivation. We propose that male meiosis occurs amid global reprogramming of 3D chromatin organization and that strengthening of chromatin compartmentalization takes place in spermiogenesis to prepare the next generation of life.
Selection for longer lived sperm within ejaculate reduces reproductive ageing in offspring
These results demonstrate that within‐:ejaculate variation in sperm phenotype contributes to individual variation in animal life histories in the two sexes and may have important implications for assisted fertilization programs in livestock and humans.
'Old' sperm produces healthier offspring [if you are a zebrafish!]
Research shows that sperm that live for longer before fertilizing an egg produce healthier offspring. What's more, these offspring go on to have longer, healthier lifespans and in turn produce more and healthier offspring themselves. It was assumed that it doesn't matter which sperm fertilizes an egg. But this shows that there are massive differences between sperm and how they affect offspring. The research was carried out in zebrafish but may ha
How 3D arrangement of DNA helps perpetuate the species
Study reveals crucial developmental period for father's ability to produce offspring
From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear. Using new technology to reveal the 3D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations.
Virtus Health (ASX:VRT) CEO Sue Channon.
IVF giant Virtus treading water but chief Sue Channon says it can fight off the discount [This link may be from a sponsor]
Australia’s largest in vitro fertilisation provider Virtus Health appears to be treading water based on its half-year financial results, but CEO Sue Channon says a string of recent investments has it well-placed to deliver growth. Revenue at Virtus Health (ASX:VRT) was up 5 per cent to $140 million and profit took a hit, down 14 per cent to $14.9 million.
Business Announcements / [Posted:21/2/2019] / [Source:stockhead.com.au] Viewed: 881
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Title
Preimplantation embryos sex ratios in couples with four or more children of same sex,
Summary
Comment
Abstract|
Our aim was to assess the preimplantation embryos’ sex ratios in couples with four or more children of same sex, undergoing sex selection for nonmedical reasons. We conducted a cohort-historical study of all consecutive patients admitted to the IVF-PGD program in a large tertiary center. We reviewed the computerized files of all consecutive women admitted to our IVF for sex selection for nonmedical reasons. Patients and their PGD cycle characteristics were compared according to the desired sex of their embryo and the mode of fertilization. |Nine patients underwent a total of 19 PGD cycle attempts during the study period. Of the 77 embryos with complete molecular diagnosis, 41 revealed a male embryo and 36 a female embryo. Thirty-five percent of all the diagnosed embryos were of the desired sex. For couples desiring a boy, IVF cycles achieved a higher ratio of the desired embryonal sex compared to ICSI (52% vs 18.7%). |For couples desiring a girl, ICSI cycles had a higher percentage of the desired embryonal sex compared to IVF cycles (38% vs 23%). Moreover, 29.7% of ICSI and 40% of IVF embryos achieved the desired sex. In conclusion, PGD for sex selection results in a relatively low percentage (35%) of embryos demonstrating the desired sex.| Nonetheless, selecting the mode of fertilization (ICSI/IVF) might improve the success rate. Further studies are required to explore the appropriate and cost-effective method for sex selection for nonmedical reasons.
IVF Training - Questions relating to mailout links -
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There was a difference between no marijuana exposure and either past or current smoking
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IVFLabOnline - Recent Enteries to IVFLabOnlines product listings.see IVFLabonline
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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Irvine Scientific
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