Comment:Links to the free articles in Human Reproduction on Oocytes, Zygotes, Cleavage and blastocysts descriptions.
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Blastocyst culture has also been used as a tool to select the most viable embryos in a cohort with a consequent reduction in the number of embryos transferred and the corresponding reduction in the incidence of multiple gestations.
A precise embryo quality evaluation is of paramount importance to sustain a successful in vitro fertilization (IVF) program. In most IVF clinics around the world, this quality assessment relies mainly on the morphological evaluation of cleavage stage embryos. Embryologists should be able to correlate the features observed at the optical microscope with the implantation potential of each particular embryo
A series of dynamic and complex events are triggered following sperm–oocyte interaction that sequentially leads to fertilization and the formation of a zygote. These events include sperm penetration, sperm–oocyte fusion and oocyte activation, male and female pronucleus (PN) development and gradual migration of the pronuclei (PNs) to a central position in the oocyte.
Owing to the complex mechanisms related to oocyte maturation and acquisition of competence, it is unlikely that a single characteristic (with the exception of oocyte size and the presence of SER aggregates) can adequately reflect the quality of the cell.
How Multivariate Ejaculate Traits Determine Competitive Fertilization Success in Drosophila melanogaster
Next, by competing males from different lines, we show how rival sperm significantly influence each other's velocity and reveal that males with relatively slow and/or long sperm better displace rival sperm and resist displacement, thus avoiding ejection by the female from her reproductive tract. Finally, we establish fitness consequences of genetic variation in sperm quality and its role in securing a numerical advantage in storage by showing tha
The notion of a “biological clock” in women arises from the fact that oocytes progressively decline in number to the point of exhaustion as females get older, along with a decades-old dogmatic view that oocytes cannot be renewed in mammals after birth [1]. This latter thinking was challenged in 2004 when Tilly and colleagues [2], then others [3], reported that the rate of oocyte loss through follicular atresia and ovulation was much higher than t
The changes they are a-timed: metabolism, endogenous clocks, and the timing of puberty
..recently elucidated neuroendocrine regulators of pubertal progression such as kisspeptin, explore models detailing how the mammalian reproductive axis is silenced during the juvenile period and reactivated at appropriate developmental times, and emphasize how metabolic dysfunction such as childhood obesity may alter timing cues that advance or delay pubertal progression, resulting in diminished reproductive capacity.
When it comes to sperm meeting eggs in sexual reproduction, conventional wisdom holds that the fastest swimming sperm are most likely to succeed in their quest to fertilize eggs. That wisdom was turned upside down in a new study of sperm competition in fruit flies (Drosophila melanogaster), which found that slower and/or longer sperm outcompete their faster rivals.
Published August 2 in Current Biology, research led by Monash University, describes how mutations to the DNA of the mitochondria can account for differences in the life expectancy of males and females. Mitochondria, which exist in almost all animal cells, are vital for life because they convert our food into the energy that powers the body.
Childhood Obesity May Affect Timing of Puberty, Create Problems With Reproduction
A dramatic increase in childhood obesity in recent decades may have impacts that go beyond the usual health concerns - it could be disrupting the timing of puberty and ultimately lead to a diminished ability to reproduce, especially in females.
Survey:Blastocyst Vitrification [This link may be from a sponsor]
Comment:Many clinics routinely vitrify blastocysts but there is little information on how often the cavity is collapsed before vitrification and hatched after warming. This quick survey seeks to find out how common these techniques are.
2012 IVF Laboratory Census [This link may be from a sponsor]
will improve accountability.You can submit answers linked to your IP address but they may not be utilised. REGISTER NOW
Comment:I know this is incomplete but FertAid wishes to conduct an annual census of IVF Laboratory activities. Many will not apply but please complete all questions. One reply per lab please. If you register first then you can review the results.
IVFCPD Module #8 Laboratory Controlled Aspects of IVF Culture Media [This link may be from a sponsor]
Commercial production of culture media has helped standardize this aspect of the IVF laboratory and improved quality control. However, there are still aspects of the culture media, outside of its selection, that are still directly controlled within the laboratory that can impact embryo development. These parameters include pH, temperature and osmolality. Careful attention to detail during media preparation and embryo culture are required to optim
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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