Comment:Links to articles on a universal warming protocol, data suggestion anti-oxidants play a role in oocyte viability. Explore QAPonline to review the embryo ranking EQA Programme where your staff are asked to rank up to 9 embryos each month and are then ranked against to popular choices.
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Physical activity before IVF and ICSI cycles in infertile obese women: an observational cohort study
In conclusion, regular physical activity carried out before a assisted reproduction cycle is significantly related with improved reproductive performance in obese infertile patients, irrespective of bodyweight loss.
Influence of ovarian stimulation for IVF/ICSI on the antioxidant defence system and relationship to outcome
Accordingly, women who became pregnant presented higher vitamin E concentrations both in plasma and FF than those who did not. In conclusion, this study confirmed the occurrence of significant modifications of the plasma antioxidant profile during ovarian stimulation with gonadotrophins: at the same time, it was found that both systemic and follicular antioxidant status may be related to IVF/ICSI outcome
Association between response to ovarian stimulation and miscarriage following IVF: an analysis of 124 351 IVF pregnancies
Analysis of this extensive dataset suggests that poor responders have a higher risk of clinical miscarriage, indicating that poor ovarian response is associated with a parallel decline in both oocyte quantity and quality. The miscarriage rate is also higher with advanced age, secondary infertility and a female cause of infertility compared with a younger age, male factor infertility and unexplained cause.
Triaging pregnancies of unknown location: the performance of protocols based on single serum progesterone or repeated serum hCG levels
The results show that serum progesterone is less efficient for triage than serial hCG measurements assessed using the M4 model, the striking difference being serum progesterone places nearly all IUP in the high-risk category. A two-step strategy combining single-visit and two-visit approaches should be investigated.
Pre-mixing serum samples with assay buffer is a prerequisite for reproducible anti-Müllerian hormone measurement using the Beckman Coulter Gen II assa
Our study has confirmed previous findings of lack of consistency in AMH concentrations when measured with the Gen II assay. Pre-mixing serum samples with assay buffer gave higher but also the most consistent results regardless of storage conditions: therefore, we propose that all serum samples for AMH assay should be pre-mixed with assay buffer. Furthermore, clinical laboratories that offer AMH measurement as part of the assessment of endocrinopa
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis
Adenomyosis appears to impact negatively on IVF/ICSI outcome owing to reduced likelihood of clinical pregnancy and implantation, and increased risk of early pregnancy loss. Screening for adenomyosis before embarking on medically assisted reproductive procedures should be encouraged. The potentially protective role of long down-regulation protocols needs further evaluation. In future studies on the association between adenomyosis and IVF/ICSI out
Comparative analysis of three sperm DNA damage assays and sperm nuclear protein content in couples undergoing assisted reproduction treatment
Alteration in sperm nuclear protein affects sperm DNA integrity. Further, with the current dataset, TUNEL and Comet assays appeared more predictive of ART success than FCCE.
TAp73 is essential for germ cell adhesion and maturation in testis
At the molecular level, TAp73, which is produced in germ cells, controls a coordinated transcriptional program of adhesion- and migration-related proteins including peptidase inhibitors, proteases, receptors, and integrins required for germ–Sertoli cell adhesion and dynamic junctional restructuring. Thus, we propose the testis as a unique organ with strict division of labor among all family members: p63 and p53 safeguard germ line fidelity, where
Preconception stress increases the risk of infertility: results from a couple-based prospective cohort study—the LIFE study
This is the first US study to demonstrate a prospective association between salivary stress biomarkers and TTP, and the first in the world to observe an association with infertility.
The danger of ignoring pregnancy and delivery rates in ART
We are convinced that in rediscovering the importance of quick and safe (in this order) conceptions for infertility patients (Scotland et al., 2007), our European colleagues will quickly close the still widening gap between USA and European pregnancy and delivery rates. Considering that the age of infertility patients in developed countries is steadily increasing, better ART pregnancy rates would appear particularly important.
Rapid warming increases survival of slow-frozen sibling oocytes: a step towards a single warming procedure irrespective of the freezing protocol?
The application of this warming protocol allows us to increase the efficiency of oocyte slow freezing procedure, enabling survival rates comparable with that reported in previous vitrification studies. This finding redefines the scenario of slow-frozen and vitrification, confirming the pivotal role of warming and indicating that the results obtained until now with slow-frozen oocytes/embryos can be improved: this could be the biggest breakthrough
Stress impacts ability to get pregnant, study finds
Women who have trouble getting pregnant may be under too much stress, according to a new study. According to researchers, women who had the highest levels of stress actually took 29 percent longer to get pregnant compared to other women, and their risk of infertility doubled. Researchers tracked 501 American women ages 18 to 40 years who were free from known fertility problems and had just started trying to conceive, and followed them for 12 mon
The app that lets parents see life form before their eyes: Fertility clinic creates programme that shows embryos in the lab in real-time
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Having fertility treatment can be very stressful for hopeful parents, but now one clinic has found a way of making it slightly easier. A fertility clinic in Barcelona has created an app that allows parents-to-be to see their embryos in the lab in real-time. The Institut Marquès fertility clinic offers the service to couples who are having IVF and whose embryos are being incubated in an ‘Embryoscope’. This state-of-the-art incubator contains a ca
Women who produce fewer eggs during IVF treatment are more likely to miscarry, research suggests.
Scientists analysed 124,351 IVF pregnancies between 1991 and 2008. About 20% of pregnancies in women who produced fewer than four eggs after the ovarian stimulation phase of IVF ended in miscarriage. The research indicated the quality of the eggs in these cases was poorer - clinicians said this information would help them to counsel patients
The process of producing high-quality, fertile sperm requires many steps. Researchers show the transcription factor p73 promotes this process by regulating the adhesions between developing sperm and their support cells. The p53 family of transcription factors has an ancient and well-conserved function in protecting reproductive cells.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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