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Twenty years’ experience with the Swiss data registry for assisted reproductive medicine: outcomes, key trends and recommendations for improved practi
Optimal ovarian stimulation should be designed for the retrieval of 10 to 15 oocytes per treatment. Swiss legislation should enable and stimulate a policy of elective single embryo transfer to avoid multiple births.
Aged men share the sperm protein PATE1 defect with young asthenozoospermia patients
This study revealed a common molecular basis underlying the decline in sperm quality in the natural aging process and in young men with asthenozoospermia. The data should greatly contribute to the development of molecular evaluation of sperm quality, and the diagnosis and treatment of asthenozoospermia.
Mitochondrial permeability transition increases reactive oxygen species production and induces DNA fragmentation in human spermatozoa
We propose that the MPT, due to pores opening in sperm IMM, is an important mechanism of increased ROS and DNA fragmentation. Therefore, agents that modulate the opening of these pores might contribute to the prevention of damage by oxidative stress in human spermatozoa.
No benefit of culturing embryos in a closed system compared with a conventional incubator in terms of number of good quality embryos: results from an
There was no significant difference in the mean ± SD number of GQEs between groups: 2.41 ± 2.27 for the closed system group and 2.19 ± 1.82 for the control group (P = 0.34, difference 0.23, 95% confidence interval 0.69: −:0.24). A significantly higher miscarriage rate was found in the TLI group compared with the control group (33.3 and 10.2%, P = 0.01).
Fertility Preservation for Non-Medical Reasons: Controversial, but Increasingly Common
In non-medical indications the woman concerned wishes to postpone pregnancy and childbirth, perhaps for career reasons or because she does not currently have a partner. Although medical freezing and social freezing cannot always be clearly distinguished, the risks of fertility-preserving measures as well as their efficacy have to be evaluated from the medical and ethical viewpoints.
Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibito
These results demonstrate that obesity before conception imparts a legacy of mitochondrial loss in offspring that is caused by ER stress and is reversible during the final stages of oocyte development and maturation.
Damage from obesity passed to offspring, but impact of obesity on fertility can be reversed, mouse study finds
In a breakthrough discovery, researchers have revealed how damage from obesity in mice is passed from a mother to her children, and also how that damage can be reversed.
CASE STUDY: Focus on Sperm to Achieve Better Pregnancy Rates
Irvine Scientific Promotion: With male infertility on the rise, pH and buffering capacity are playing an even more important role in the physicochemical processes that govern sperm quality, viability, and motility. For fertility clinics, optimizing sperm performance can be a key differentiating factor in achieving better pregnancy rates for their patients. In an effort to minimize variables impacting sperm, Jayant G. Mehta,
Ph.D., Lab Director a
Social freezing: The pros and cons of oocyte storage
The announcement by Apple and Facebook that they would pay for their employees to place oocytes in frozen storage - so-called social freezing - sparked a heated debate about the creation of such a fertility resource for non-medical reasons. Although discussion of the moral and social aspects predominates, the medical consequences cannot be ignored.
Fertility Associates, the leading fertility provider urgently needs an experienced Embryologist.The successful candidate must have a degree in biological sciences and will have a minimum of two years IVF/ICSI experience including embryo cryopreservation. Our embryologists are also expected to be able to carry out a wide range of Andrology services including semen cryopreservation
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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