Comment:This weeks newsletter posts links to 2 new surveys. One on embryologist training and qualifications (tell everyone about this & post on your own blogs) and secondly, draft survey for Embryologist day. Post suggestions to Liesl Nel at lnthemaat@gmail.com for final changes before voting can be available. Oh & by the way a post showing Sperm DNA damage is linked to poor outcomes after IVF BUT NOT after ICSI- hardly surprising. Does this mean we should all do ICSI or test all for Sperm DNA Damage!
Survey-2014 Laboratory Census
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Sperm DNA damage has a negative association with live-birth rates after IVF
Sperm DNA damage was also associated with low live-birth rates following IVF in both men and couples with idiopathic infertility: 39% of couples and 41% of men with idiopathic infertility have high sperm DNA damage. Sperm DNA damage assessed by the Comet assay has a close inverse relationship with live-birth rates after IVF. Following ICSI, no significant differences in sperm DNA damage were found between any groups of patients.
Selection pressures on body size often differ between the sexes across many species, including humans: among men individuals of average height enjoy the highest reproductive success, while shorter women have the highest reproductive success. Given its high heritability, IASC over human height is likely.
Extreme sex ratio variation in relation to change in condition around conception [in horses but interesting nevertheless wtr glucose]
Adaptive theory predicts that mothers would be advantaged by adjusting the sex ratio of their offspring in relation to their offspring's future reproductive success. Studies investigating sex ratio variation in mammals have produced notoriously inconsistent results, although recent studies suggest more consistency if sex ratio variation is related to maternal condition at conception, potentially mediated by changes in circulating glucose level.
High Sperm DNA Damage a Leading Cause of 'Unexplained Infertility', Research Finds
New research from Queen's University Belfast has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility'.
Drinking one or two glasses of wine a week during pregnancy can have an impact on a child's IQ, a study says. Researchers from Oxford and Bristol universities looked at the IQ scores of 4,000 children as well as recording the alcohol intake of their mothers.
Sperm Length Variation Is Not a Good Sign for Fertility
Perhaps variety is the very spice of life, but as a matter of producing human life, it could be the bane of existence. That's the indication of a new study in the journal Human Reproduction that found men with wider variation in sperm length, particularly in the flagellum, had lower concentrations of sperm that could swim well. Those with more consistently made sperm seemed to have more capable ones.
Men and Women Battle for Ideal Height: Evidence of an Intralocus Sexual Conflict Currently Raging in Human DNA
A battle about the ideal height would appear to be raging in men's and women's genes. Gert Stulp, PhD candidate at the University of Groningen, has shown that this conflict is leading to a difference in reproductive success between men and women of varying height
Survey:World Embryologists Day - review & comment on questions.
Comment:Liesl Nel-Themaat of Colorado Reproductive Endocrinology posted on EmbryoMail the idea of holding an regular Embryologists Day. While it is under development, contact Liesl Nel at lnthemaat@gmail.com with ideas and suggestions. When approved, it will be available for submissions.
1st INTERNATIONAL WORKSHOP ON TROUBLESHOOTING IN ASSISTED REPRODUCTIVE TECHNOLOGIES.
MAIN GOAL: Participants will learn to develop strategies for troubleshooting, problem solving and global quality management. The course includes practical applications of physical and chemical laws related to cell culture. Students will be made familiar with troubleshooting via role-playing exercises in which the participants assume the role of characters in a fictional setting based on real laboratory
issues from past scenarios.
Expanded Halosperm EQA program. [This link may be from a sponsor]
An EQA/Competency schemes for the assessment of sperm DNA fragmentation by the Halospem method. This has been expanded to 12 data sets for 2013 with images form several users. Participants are shown 20+ sets of images from one sample and asked to estimate the number Normal and abnormal sperm ( according to the methodology) and calculate a % DFI
Sperm DNA Fragmentation SURVEY [This link may be from a sponsor]
Assessment of Sperm DNA Fragmentation by TUNEL, SCSA, halosperm or other appear very popular but is it? Complete the survey to find out just how many clinics are performing this assay. [Tell your fellow scientists to complete this survey!!]
Lewis Fertility Testing can help you !!!! [This link may be from a sponsor]
We have pioneered a test that quickly and effectively evaluates the DNA quality of sperm. Using our SpermComet™ technology, this unique test gives accurate information never available through conventional semen analysis. This test can help clinics to tailor treatment specifically to the man's needs.
Mammalian oocytes occupy a critical nexus in reproduction as they not only contribute half the genetic makeup of the embryo but also provide virtually all of the cytoplasmic building blocks required for sustaining embryogenesis.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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