There are 0 comments attached to this mailout - Review Comments
If you would like to receive weekly mail digest please Register
OR Forward this mail to a friend
IVFDaily Mail out is about distribution of educational, professional, industry news and product information. If you are a manufacturer or a distributor and wish to make recipients of FertAid Mail aware of your product, please submit a web link here CONTRIBUTE. Listing on IVFdaily.com is Free but inclusion in the mailout attracts a small fee.
From June, 2014 forward, FertAid is developing an online forum for all IVF Clinic Staff. Called IVFClinicMail. When you see this icon against a link, it means there is a comment(s) attached to it. Feel free to click on the icon and contribute.
Jobs
IVFDaily has now provided the tool to advertise any jobs FREE . Simply post the job information as a PDF to office@fertaid.com Listing a position on IVFdaily.com is Free but inclusion in the mailout attracts a small fee.
IVFD
If you receive this distribution by email, then when you click on any link, this linkage will be tagged to your selection list so you can always find it again after you have logged on OR you can click on to mark the link in your file.
Worldwide decline of IVF birth rates and its probable causes
Over the past decade and a half, IVF, therefore, has increasingly disappointed outcome expectations. Remarkably, neither the profession nor the public have paid attention to this development which, therefore, also has gone unexplained. It now urgently calls for evidence-based explanations.
The effect of repeated controlled ovarian stimulation cycles on the gamete and embryo development
Repeated COS does not seem to have any adverse effect on ovarian response to higher dose of artificial gonadotropin, as quality of oocytes collected and their embryological developmental potential were not affected by the number of successive stimulation cycles. The effect of multiple COS on the health of the oocyte donor needs to be assessed for future purpose.
Blastocyst biopsy and vitrification are required to efficiently conduct preimplantation genetic testing. An approach entailing the sequential opening of the zona pellucida and retrieval of 7-8 trophectoderm cells in day 5-7 post-insemination limits both the number of manipulations required and the exposure of the embryo to sub-optimal environmental conditions.
Advanced sperm selection techniques for assisted reproduction
The evidence suggests that sperm selected by hyaluronic acid binding may have little or no effect on live birth or clinical pregnancy but may reduce miscarriage. We are uncertain of the effect of Zeta sperm selection on live birth, clinical pregnancy, and miscarriage due principally to the very low quality of the evidence for this intervention. We are uncertain of the effect of the other selection techniques on live birth, miscarriage, or pregnan
Intracytoplasmic morphologically selected sperm injection, but for whom?
Results were analysed to evaluate the effects of the IMSI procedure and to find the most suitable group of patients who may benefit from the procedure. IMSI caused a significant increase in the fertilization and top quality embryo rates in the male infertility group and a significant increase in fertilization and pregnancy rates in the repeated implantation failure group, whereas no effect was observed in the non-selected group with patients of v
Embryo donation: Survey of in-vitro fertilization (IVF) patients and randomized trial of complimentary counseling
Conclusion
Improvement in counseling rates over the control arm suggests that free professional counseling is a small, but likely effective, step towards deciding on an EDO.
Subsidizing PGD: The Moral Case for Funding Genetic Selection
We examine the objections to our proposal, specifically concerns regarding designer babies and the harm of disabled individuals, and show why these are substantially outweighed by arguments for subsidizing PGD. We argue that an acceptance of PGD is aligned with present attitudes towards procreative decision making and IVF use, and that it should therefore receive government funding.
Births from embryos with highly elevated levels of mitochondrial DNA
Conclusions: Measurement of mtDNA copy number might not provide any advantage in embryo prioritization and could lead to a deselection of blastocysts that would result in healthy pregnancies and births. Furthermore, the quantification of mitochondrial functional output in a model of cellular stress might suggest that mitochondria are not clear targets for biomarker identification as it relates to blastocyst viability. Any suggested link between m
Does a microfluidic chip for sperm sorting have a positive add‐::on effect on laboratory and clinical outcomes of intracytoplasmic sperm injectio
No statistically significant differences were found between groups in terms of all outcomes analysed in laboratory and clinical terms (p > .05 for all). The results of this study suggest that sorting spermatozoa through Fertile chip does not improve laboratory outcomes significantly and does not seem to have a positive contribution to clinical outcomes.
Performance of Day 5 KIDScore™ morphokinetic prediction models of implantation and live birth after single blastocyst transfer
KIDScore™ Day 5 predictive models are significantly associated with implantation rates after day 5 single blastocyst transfer. However, their predictive performance remains perfectible. The use of these predictive models holds promises as decision-making tools to help the embryologist select the best embryo, ultimately facilitating the implementation of SET policy. However, embryologists’ expertise remains absolutely necessary to make the final d
Human Blastocyst Biopsy and Vitrification.[Abstract]
Summary
Abstract of JoVE video article.
Comment
Abstract.|Blastocyst biopsy is performed to obtain a reliable genetic diagnosis during IVF cycles with preimplantation genetic testing. Then, the ideal workflow entails a safe and efficient vitrification protocol, due to the turnaround time of the diagnostic techniques and to transfer the selected embryo(s) on a physiological endometrium in a following natural cycle. A biopsy approach encompassing the sequential opening of the zona pellucida and retrieval of 5-10 trophectoderm cells (ideally 7-8) limits both the number of manipulations required and the exposure of the embryo to sub-optimal environmental conditions. |After proper training, the technique was reproducible across different operators in terms of timing of biopsy (~8 min, ranging 3-22 min based on the number of embryos to biopsy per dish), conclusive diagnoses obtained (~97.5%) and live birth rates after vitrified-warmed euploid blastocyst transfer (>40%). The survival rate after biopsy, vitrification and warming was as high as 99.8%. The re-expansion rate at 1.5 h from warming was as high as 97%, largely dependent on the timing between biopsy and vitrification (ideally less than 30 min), blastocyst morphological quality and day of biopsy. |In general, it is better to vitrify a collapsed blastocyst. Therefore, in non-PGT cycles, laser-assisted artificial shrinkage might be performed to induce embryo collapse prior to cryopreservation. The most promising future perspective is the non-invasive analysis of the IVF culture media after blastocyst culture as a putative source of embryonic DNA. However, this potential avant-garde is still under investigation and a reliable protocol yet needs to be defined and validated. |Note this link is to a subscription based video on vitrification.|
IVFLabOnline - Recent Enteries to IVFLabOnlines product listings.see IVFLabonline
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
New Developments at FertAid during
July, 2025 and July, 2025
No News
FertAid Functions.
EQA
A range of online Quality Assurance Modules
IVFDaily
New Articles in Press and Interesting, relevant News Items, Business News and other mail
IVFCPD
New education modules
Logbooks
Free Online logbook for IVFLaboratory and Nursing Staff
KPI Benchmarking
New to FertAid. This modules allows ANONYMOUS monthly KPI data entry, management of warning and action limits and anonymous comparisons with country and defined KPI sub-groups
Business
Unlike other mailgroups, IVFDaily will distibute recent business news or developments of interest to IVF staff
to mark the link in your file.
