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Mail Name:IVFDaily 2019.37 EQA-Time Lapse Assessment
Distribution: 8346-8355 Posted 2/1/2020 Embryo Ranking Challenge-Invitation
Comment: Survey-2014 Laboratory Census
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IVFD Informing offspring of their conception by gamete or embryo donation: an Ethics Committee opinion [2018]
Because of each person's fundamental interest in knowing their genetic heritage and the importance of their ability to make informed health-care decisions in the future, the Ethics Committee supports disclosure about the fact of their donor conception to offspring. It also supports the gathering and storage of medical and genetic history information that can be provided to offspring if they request
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- View Link - Keywords: disclosure offspring donor informing offspring of their conception
Publications / [Posted:26/12/2019] / [Source:www.fertstert.org] Viewed: 930
IVFD Age-associated sperm DNA methylation patterns do not directly persist trans-generationally
This study suggests that the robust and consistent age-associated methylation alterations seen in human sperm are ‘reset’ during large-scale epigenetic reprograming processes and are not directly inherited trans-generationally (over two generations). An extremely small trend was present between the YGPA and OGPA groups that resemble the aging pattern in older sperm. However, this trend was not significant and was so small that, if real, is almost
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- View Link - Keywords: male age epigenetics sperm age-associated methylation age-associated sperm dna methylation patterns
Publications / [Posted:26/12/2019] / [Source:epigeneticsandchromatin.biomedcentral.com] Viewed: 878
IVFD Oxidative stress in sperm affects the epigenetic reprogramming in early embryonic development
Conclusions The data demonstrate that oxidative stress in [cattle] sperm has an impact not only on DNA integrity but also on the dynamics of epigenetic reprogramming, which may harm the paternal genetic and epigenetic contribution to the developing embryo and affect embryo development and embryo quality.
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- View Link - Keywords: ROS DNA demethylation embryonic development epigenetic reprogramming Oxidative stress
Publications / [Posted:26/12/2019] / [Source:epigeneticsandchromatin.biomedcentral.com] Viewed: 826
IVFD Levels of caspase-3 and histidine-rich glycoprotein in the embryo secretome as biomarkers of good-quality day-2 embryos and high-quality blastocysts
In conclusion, in future prediction models, levels of caspase-3 and HRG might be used as potential markers of embryo quality, and secreted caspase-3 levels could to some extent predict the outcome after transfer of day-2 cultured embryos.
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- View Link - Keywords: embryo secretome caspase-3 histidine-rich glycoprotein embryo quality embryo markers embryo selection
Publications / [Posted:26/12/2019] / [Source:journals.plos.org] Viewed: 847
IVFD The incidence of hypertensive disorders of pregnancy following sperm donation in IVF: an Australian state-wide retrospective cohort study
These findings suggest that exposure to new sperm may not be implicated in the pathogenesis of preeclampsia. The mechanism of increased risk seen in conceptions arising from egg or embryo donation remains unclear. Further investigation is required to elucidate these mechanisms and, ultimately, improve pregnancy outcomes following IVF
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- View Link - Keywords: donor sperm preeclampsia primipaternity ivf icsi fetal growth restriction
Publications / [Posted:30/12/2019] / [Source:academic.oup.com] Viewed: 1158
IVFD Effect of a 6-week “Mediterranean” dietary intervention on in vitro human embryo development: the Preconception Dietary Supplements in Assisted Reprod
Result(s): There was no difference in CC2 between the two groups. However, CC4 was accelerated in the study group compared with the control group, and a significantly shortened S3 as well as an increase in KIDScore on day 3 were observed, indicating improved embryo quality in the study group.
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- View Link - Keywords: diet omega-3 ivf morphokinetic markers embryo development diet and embryo development
Publications / [Posted:30/12/2019] / [Source:www.fertstert.org] Viewed: 1522
IVFD Functional Oocytes Derived from Granulosa Cells
Here, we show that somatic granulosa cells isolated from adult mouse ovaries can be robustly induced to generate gPSCs by a purely chemical approach, with additional Rock inhibition and critical reprogramming facilitated by crotonic sodium or acid. These gPSCs acquired high germline competency and could consistently be directed to differentiate into primordial-germ-cell-like cells and form functional oocytes that produce fertile mice.
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- View Link - Keywords: granulosa cells oocytes pluripotent stem cells functional oocytes derived from granulosa cells
Publications / [Posted:2/1/2020] / [Source:www.cell.com] Viewed: 801
IVFD Fewer fats over the festive season may be the perfect formula for men's fertility - Egg whites and whey protein boost testosterone
A diet low in fat and high in egg whites could be the key to boosting male fertility according to a new pilot study.
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- View Link - Keywords: macronutrients protein testosterone overweight obese
News Articles / [Posted:2/1/2020] / [Source:www.sciencedaily.com] Viewed: 1734
IVFD Chinese scientist He Jiankui, who 'gene-edited' babies, jailed for practising medicine illegally
Chinese scientist He Jiankui, who claimed he made the world's first "gene-edited" babies by altering human embryos in 2018, has been convicted on charges of practising medicine illegally, according to Chinese state media.
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- View Link - Keywords: gene editing "gene-edited" babies gene-edited babies gene-edited babies
News Articles / [Posted:30/12/2019] / [Source:www.abc.net.au] Viewed: 1008
IVFD Mouse pups born from eggs derived from the granulosa cells that surround oocytes
By introducing a chemical cocktail to granulosa cells, researchers induced the cells to transform into functional oocytes in mice. Once fertilized, these oocytes were then successfully able to produce healthy offspring, showing no differences from naturally bred mice.
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- View Link - Keywords: granulosa cells oocytes pluripotent stem cells
News Articles / [Posted:2/1/2020] / [Source:www.sciencedaily.com] Viewed: 1077

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IVF Training - Questions relating to mailout links - Open Challenge and complete Questions
Question Type Options
Which cell cycle was completed sooner after dietrary supplementation 1 4
Which KIDScore (from time lapse monitoring) was increased after dietary supplementation. 1 5

IVFLabOnline - Recent Enteries to IVFLabOnlines product listings. see IVFLabonline
Product
Aire-Alert View
Description
Live Monitoring,PPB Volatile Organic Compounds (VOC),Temperature,Relative Humidity. (no web link available).  
Source
LifeAire Systems
   
Product
Aire-LifeLine View
Description
In-line filter for cylinder and house gasses O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med  
Source
LifeAire Systems
   
Product
Vit Kit - Warm NX Catalog ID: 90183 View
Description
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med  
Source
Irvine Scientific
   
Product
Vit Kit - Freeze NX View
Description
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t  
Source
Irvine Scientific
   
Product
S-CRYOLOCK - Blue Vitrification device View
Description
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.  
Source
Irvine Scientific
   

New Developments at FertAid during July, 2025 and July, 2025
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FertAid Functions.
EQA
A range of online Quality Assurance Modules
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New Articles in Press and Interesting, relevant News Items, Business News and other mail
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New to FertAid. This modules allows ANONYMOUS monthly KPI data entry, management of warning and action limits and anonymous comparisons with country and defined KPI sub-groups
Business
Unlike other mailgroups, IVFDaily will distibute recent business news or developments of interest to IVF staff

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