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The Cytogenetic Constitution of Human Blastocysts: Insights From Comprehensive Chromosome Screening Strategies
These findings do not support the notion that mosaic chromosome abnormalities are a natural part of embryo development. Mosaic aneuploidies, arising post-zygotically, were detected by various different comprehensive molecular cytogenetic methods, suggesting that the majority of these represent genuine findings.
Embryo Biopsy Can Offer More Information Than Just Ploidy Status
As a byproduct of increasing infertility cases, the use of medically assisted reproduction (MAR) has increased. As such, the need to gain information regarding the implantation potential of specific MAR preimplantation embryos prior to transfer has become increasingly critical. One potential source of this information is contained in the blastocoel fluid from day 5/6 embryos
Managing the IVF laboratory during a pandemic: International perspectives from laboratory managers
The intention of this paper is to collect the learnings and considerations from this group of lab managers who collaborated to share personal experiences to contribute to the debate surrounding what constitutes good IVF laboratory practice in extraordinary circumstances, such as the Covid-19 pandemic.
Maternal and perinatal outcomes with COVID 19 A systematic review of 108 pregnancies
Although the majority of mothers were discharged without any major complications, severe maternal morbidity as a result of COVID‐::19 and perinatal deaths were reported. Vertical transmission of the COVID 19 could not be ruled out. Careful monitoring of pregnancies with COVID 19 and measures to prevent neonatal infection are warranted.
The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution
The history ends with a glimpse of the future: minimally/non-invasive PGT and experimental embryo micromanipulation protocols. This grand theme review outlines a timeline of the evolution of embryo biopsy protocols, whose implementation is increasing worldwide together with the increasing application of PGT techniques in IVF
Next-generation sequencing analysis of each blastomere in good-quality embryos- insights into the origins and mechanisms of embryonic aneuploidy in cl
In good-quality embryos, there was a high rate and diverse array of chromosomal abnormalities. Morphological evaluation does not appear to assist in the reduction in meiotic errors from parental origins. Mitotic errors were common, and nondisjunction was found to be the main mechanism causing malsegregation during the cleavage divisions.
Antioxidants increase [mouse] blastocyst cryosurvival and viability post-vitrification
Results in this study demonstrate that vitrification and warming of blastocysts have significant detrimental effects on embryo histone acetylation and subsequent viability. The presence of antioxidants in the vitrification solutions helps to alleviate the negative effects of cryopreservation.
What the latest research suggests about the coronavirus in pregnancy [New Scientist]
A GROWING number of case studies suggest that, while pregnant people don’t seem to be at greater risk of the coronavirus, covid-19 is linked to a higher rate of caesareans and preterm births, and the virus may be able to cross the placenta to a fetus.
Webinar - Optimizing your embryo culture system [2018]
In this webinar, Steve Levett, PhD provides an introduction to factors affecting embryo culture, including pH and osmolality, and how these can be optimized in the clinical IVF laboratory. Sponsor is CooperSurgical Fertility and Genomic Solutions
Implantation requirements: Embryo competency and endometrial receptivity
CooperSurgical Fertility and Genomic Solutions. In this webinar, Mike Large, PhD, Senior Director for Research and Development (Genomics) at CooperSurgical introduced participants to the key aspects of the embryo-endometrium relationship. He covers topics including signaling between the embryo and endometrium, the role of cytokines/growth factors and the importance of euploid embryo and receptive endometrium in maximizing implantation and ongoing
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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