Comment:FertAid has introduced a Trading Post section to allow scientists to post or enquire after used IVF equipment. There are 3 listings in this release. Unlike Embryomail that is purely for non-commercial posts, IVFDaily and IVFLabonline/Trading Post is available to companies to post new developments or important commercial information. Enjoy. There are also posts on the negative effects of post ET bed rest; day 3 biopsies and the use of ICSI after failed fertilisation.
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Increased risk of preterm birth in singleton pregnancies after blastocyst versus Day 3 embryo transfer: Canadian ART Register (CARTR) analysis
Preterm birth rate <37 weeks (unadjusted by potential confounding factors) was higher with Day 5/6 versus Day 3 transfers (17.2 versus 14.1%, P < 0.001). Using logistic regression analysis to adjust for confounding factors, preterm birth rate <37 weeks was the only outcome significantly increased after Day 5/6 compared with Day 3 transfer (odds ratio 1.32, 95% confidence interval 1.17–1.49).
Extended culture and the risk of preterm delivery in singletons: confounding by indication?
We read with interest the recent article (Dar et al., 2013) suggesting that singletons born after extended culture may have a higher risk of preterm delivery than those born after Day 3 transfer. While the importance of optimizing embryo culture and improving obstetrical outcomes after in vitro fertilization should not be underestimated, we believe this study suffers from a serious methodological flaw, namely ‘confounding by indication’.
Reply: Extended culture and the risk of preterm delivery in singletons: confounding by indication?
We read the above letter with interest and thank Drs Forman, Werner and Scott for their comments. We naturally agree that the goal of assisted reproduction techniques is a healthy baby, born at term, and that elective single embryo transfer (eSET) is the best way to avoid multiple pregnancy and its associated risk of preterm delivery and other complications.
Among 20 HMs, 3 showed the genotype PPPM: one with the sex chromosomes XXYY and two with XXXY, indicating that they originated in tetraploid zygotes. In 14 androgenetic, one likely androgenetic and two mosaics, the tetraploid cells likely developed by endoreduplications of diploid cells. One case did not fulfil the histopathological criteria for HM.
Genotoxicity assessment of mouse oocytes by comet assay before vitrification and after warming with three vitrification protocols
Vitrification protocols containing PrOH induced significant DNA damage on mouse oocytes, both before cooling and after warming. Therefore, for the moment, we prefer vitrification techniques without PrOH while we await more studies on PrOH toxicity and long-term evaluation.
Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial
The statistically significant higher LBI rate shown in our NR group confirms that 10 minutes of bed rest immediately after ET has no positive effect and in fact can be negative for the outcome of IVF with OD. The anatomical/physiological or psychological reasons for this should be explored in future research.
Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical
Blastomere biopsy on day 3 of development resulted in a significant reduction in sustained implantation. Only 30% of biopsied embryos had sustained implantation and ultimately developed into live-born infants versus 50% of unbiopsied controls, a relative reduction of 39%. In contrast, sustained implantation rates were equivalent (51% vs. 54%) for biopsied and control blastocysts.
Does intracytoplasmic sperm injection improve the fertilization rate and decrease the total fertilization failure rate in couples with well-defined un
This meta-analysis favors the use of ICSI to increase fertilization rates and decrease the risk of TFF in couples with well-defined unexplained infertility. Further studies are needed to determine the impact on clinical pregnancy and live birth rate.
Men with azoospermia have an increased risk of subsequently developing cancer, suggesting a possible common etiology between azoospermia and cancer development. Additional follow-up of azoospermic men after reproductive efforts end may be warranted.
Men Who Can't Produce Sperm Face Increased Cancer Risk
Men who are diagnosed as azoospermic - infertile because of an absence of sperm in their ejaculate - are more prone to developing cancer than the general population, a study led by a Stanford University School of Medicine urologist has found. And a diagnosis of azoospermia before age 30 carries an eight-fold cancer risk, the study says.
Slim women have a greater risk of developing endometriosis than obese women
Women with a lean body shape have a greater risk of developing endometriosis than women who are morbidly obese, according to the largest prospective study to investigate the link.
Fertility after ectopic pregnancy: first randomised trial finds reassuring evidence on the effect of different treatments
The first randomised trial to compare treatments for ectopic pregnancies has found no significant differences in subsequent fertility between medical treatment and conservative surgery on one hand, and conservative or radical surgery on the other.
QFG is looking for an experienced embryologist to be based within QFG’s Gold
Coast laboratory. This permanent position, involves participation in the
Embryology Roster, which includes weekend and public holiday work, with final
hours by negotiation with the successful candidate.
Seeking a Used laser for Nikon Diaphot [Trading Post]
Comment: I am looking for a used laser compatible with a Nikon Diaphot 200.
Details: If you have acquired a new Lykos to replace your Zilos, I would like to purchase the Zilos or the Octax is also compatible. Please email jamesary@gmail.comor call 1-949-640-7200. Thanks. Jim Ary
Used IVF lab equipment is needed to set up an IVF lab in Asia
Particularly interested in micromanipulation equipment. Peter Burton PhD Scientific Director Concept Fertility Centre 218 Nicholson Rd Subiaco 6008 +61 8 9382 2388 (Perth Western Australia)
Looking to sell the Immulite 2000 or trade for a set of micromanipluators.
We have a 6 year old Immulite 2000 available for sale or trade. The machine works perfectly and is in like new condition. All service, records, and QC are up to date. It was just taken out of service last month. I'm happy to answer any questions about the machine or it's history. We are looking for the best reasonable offer or will consider a trade for a complete set of ICSI micromanipulators in good condition. Gerard Celia, PhD, TS/HCLD (AAB) La
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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Irvine Scientific
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