Comment:Links to articles on cell competition within an implanted embryo, mothers influence the gender of the their children and much more. welcome to the new subscribers from the ESHRE meeting.
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The United Kingdom’s decision to trial the technique of mitochondrial replacement is premature and ill-conceived, says Marcy Darnovsky. The UK government’s recent move towards human trials of mitochondrial-replacement techniques has prompted intense interest among scientists and bioethicists, while the media continue to frame mitochondrial replacement as a matter of ‘three-parent babies’. The description is accurate — it would involve a woman aff
Myc-driven endogenous cell competition in the early mammalian embryo
During normal development we found that Myc levels are intrinsically heterogeneous among epiblast cells, and that endogenous cell competition refines the epiblast cell population through the elimination of cells with low relative Myc levels. These results show that natural cell competition in the early mammalian embryo contributes to the selection of the epiblast cell pool.
Macrophages regulate corpus luteum development during embryo implantation in mice
These data indicate a critical role for macrophages in supporting the extensive vascular network required for corpus luteum integrity and production of progesterone essential for establishing pregnancy. Our findings raise the prospect that disruption of macrophage-endothelial cell interactions underpinning corpus luteum development contributes to infertility in women in whom luteal insufficiency is implicated.
Winning the Genetic Lottery: Biasing Birth Sex Ratio Results in More Grandchildren
To our knowledge, these results are the first formal test of the hypothesis that birth SR manipulation is adaptive in mammals in terms of grandchildren produced, showing that SR manipulation can explain biased birth SR in general across mammalian species. These findings also have practical implications: parental control of birth SR has the potential to accelerate genetic loss and risk of extinction within captive populations of endangered specie
Egg Banking for Social Reasons: Women Feel Positive About It, Even Though Many Believe They Will Never Use the Eggs They Have Stored
Egg freezing as insurance against age-related infertility is a growing trend in many countries. Women who bank oocytes for use at some time in the future hope to buy a little time in their search for a suitable partner.
IVF for 200 Euro Per Cycle: First Real-Life Proof of Principle That IVF Is Feasible and Effective for Developing Countries
A study performed in Belgium has shown that low-cost IVF for developing and poor resource countries is feasible and effective, with delivery rates not much different from those achieved in conventional IVF programmes. This proof-of-principle study, say the investigators, suggests that infertility care may now be "universally accessible."
Early Life and in Utero Factors Found to Influence Testicular Function in Adulthood
Studies over the past 20 years have suggested that semen quality is in decline, reflected most evidently in falling sperm counts and reduced sperm motility. The explanations have been controversially attributed to environmental factors (such as exposure to toxins) and to male smoking. Now, a new study based on a 20-year follow-up of one of the world's largest study cohorts, suggests that exposure to several factors in utero and in early life may
Mammals Can 'Choose' Sex of Offspring, Study Finds
A new study led by a researcher at the Stanford University School of Medicine shows that mammalian species can "choose" the sex of their offspring in order to beat the odds and produce extra grandchildren.
Cells in the Early Embryo Battle Each Other to Death for Becoming Part of the Organism
Spanish researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have found that during the early stages of mammalian development, embryonic cells embark on a battle for survival. Through this battle, the less active of these cells are eliminated by their stronger sisters.
A baby has been born in the US using a new method for screening embryos during IVF which could dramatically reduce costs, researchers report. Connor Levy was born in May after the test, devised at Oxford University, helped doctors pick an embryo with the best chance of success.
Five million "test tube babies" have now been born around the world, according to research presented at a conference of fertility experts. Delegates hailed it as a "remarkable milestone" for fertility treatments.
Viewpoints: What does the future of IVF look like?
As the government gives the green light to an IVF technique using DNA from three people, which could eliminate some diseases passed from mother to child, the world top fertility experts gather in London to discuss the latest advances in reproductive medicine.
Why Some Women Don't Have Enough Breastmilk for Baby: Important Role of Insulin in Making Breast Milk Identified
Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating insulin's role in lactation success.
Large UK Population Study Finds No Increased Cancer Risk in Children Born After Assisted Conception
Children born as a result of assisted reproduction (ART) are at no greater risk of cancer than children born spontaneously in the general population, according to results of one of the largest ever cohort studies of ART children. "This is reassuring news for couples considering assisted conception, their subsequent children, fertility specialists and for the wider public health," said the investigators.
Women Working Shifts Are at Greater Risk of Miscarriage, Menstrual Disruption and Subfertility
Shift work, which encourages sleep deprivation and patterns of activity outside the circadian rhythm, has been associated with a greater risk of ill health and loss of well-being in some (but not all) studies. However, little is known about the effects of shift work on reproductive health and fertility.
New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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