Comment:Includes recent release from the J Assist Reprod & Genetics.
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Length of human pregnancy and contributors to its natural variation
Human gestational length varies considerably even when measured exactly (from ovulation). An individual woman's deliveries tend to occur at similar gestational ages. Events in the first 2 weeks after conception are predictive of subsequent pregnancy length, and may suggest pathways underlying the timing of delivery.
The success of assisted reproduction technologies in relation to composition of the total regulatory T cell (Treg) pool and different Treg subsets
Our findings suggest that Tregs, especially the naïve CD45RA+-Treg subset, may play a role in determining the probability of both becoming pregnant and maintenance of the pregnancy.
Sperm quality and its relationship to natural and assisted conception: British Fertility Society Guidelines for practice.
Reports on the influence of semen parameters on natural or assisted pregnancy are contradictory, suggesting that the many confounding variables which contribute to outcome have not been taken into account. However, it is possible to derive some consensus for both natural and assisted conception by focussing on studies which use WHO-recommended semen analysis on relatively large populations, applying appropriate statistics and accounting for ‘fema
Controlled ovarian hyperstimulation regimens: a review of the available evidence for clinical practice. On behalf of the British Fertility Society P&P
The GnRH antagonist protocol is best used for known or suspected high responders, including women with PCOS, as it reduces the risk of OHSS. There is a lack of robust evidence to suggest that the GnRH agonist protocol is better than the GnRH antagonist protocol in poor responders. The prolonged GnRH agonist protocol is advantageous in women who are undergoing COH due to pelvic endometriosis. Oral contraceptive pill pre-treatment adversely affects
Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months
Compared with breastfed infants, formula-fed infants had increased richness of species, with overrepresentation of Clostridium difficile. Escherichia–Shigella and Bacteroides species were underrepresented in infants born by cesarean delivery. Infants born by elective cesarean delivery had particularly low bacterial richness and diversity.
Sex ratios among Canadian liveborn infants of mothers from different countries
Interpretation: Our study of male:female ratios in Ontario showed that multiparous women born in India were significantly more likely than multiparous women born in Canada to have a male infant.
Chronological age vs biological age: an age-related normogram for antral follicle count, FSH and anti-Mullerian hormone
AMH predicted biological age earlier than FSH or AFC. Normograms can provide a reference guide for physicians to counsel infertile women. However, future validation with longitudinal data is still needed.
Determining an anti-mullerian hormone cutoff level to predict clinical pregnancy following in vitro fertilization in women with severely diminished ov
AMH of 0.2 ng/mL appears to be a meaningful threshold for predicting CPR in women with severe DOR at our practice. This information can be crucial during the pre-cycle counseling of these women.
The combination of pronuclear and blastocyst morphology: a strong prognostic tool for implantation potential
These findings suggest that a lower oocyte yield may lead to higher-quality PN zygotes. In addition, different PN features may influence further embryo development, especially the quality of the blastocyst. Moreover, the association between PN and blastocyst morphology may be used as a prognostic tool for implantation.
Oocyte cryopreservation: searching for novel improvement strategies
Conclusion: Oocyte cryopreservation has improved dramatically in recent years and is receiving widespread clinical use. Novel approaches to further improve success, as well as improved methods to assess this success will aid in continued improvement.
The heat is on: room temperature affects laboratory equipment–an observational study
There was a direct relationship between room temperature and equipment temperature stability. When room temperature increased or decreased, equipment temperature reacted in a corresponding manner. Statistical differences between equipment were found when the room temperature changed. What is also noteworthy is that temperature of equipment responded within 5 min to a change in room temperature.
Emergency IVF for embryo freezing to preserve female fertility: a French multicentre cohort study
According to literature, malignant disease is a risk factor for a poor response to COS. However, patients having emergency IVF before gonadotoxic treatment have a reasonable chance of pregnancy after embryo replacement. Embryo freezing is a valuable approach that should be included among the strategies used to preserve fertility.
Scientists say test tube-babies could be made for 200 euros with lab the size of a shoebox. LONDON (AP) — Since the first test-tube baby was born more than three decades ago, in vitro fertilization has evolved into a highly sophisticated lab procedure. Now, scientists are going back to basics and testing a simpler and cheaper method. In the West, many would-be parents spend thousands of dollars for IVF, which involves pricey incubators and extens
How Females Choose the 'Right' Sperm [fish species!]
University of East Anglia scientists have revealed how females select the 'right' sperm to fertilize their eggs when faced with the risk of being fertilized by wrong sperm from a different species.Researchers investigated salmon and trout, which fertilize externally in river water. The two species occasionally hybridize in the wild, but since hybrid offspring become reproductive dead-ends, females of both species are under selection to avoid hyb
Kelly Burke, now 45, struggled with infertility before deciding to adopt an embryo in order to have a child—and not just any embryo, but one frozen 18 years ago. A couple in Oregon who went through IVF to have twins in 1994 (themselves using donated eggs) had decided to donate their four remaining embryos. Burke, a NASA research scientist living in Virginia Beach, adopted the embryos in a "rigorous" process last year: son Liam James was born in
California: Bill to allow women to sell eggs for research is vetoed
The Governor of California, Jerry Brown, has vetoed a bill that would have allowed women to sell their eggs for medical research. The bill's author, Susan Bonilla, said a lack of research into fertility was affecting thousands of women in California who face the decision of having to store their eggs for fertility reasons.
Report Shows Huge IVF Failure: 3.8 Million Embryos Produce Just 122,000 Babies
The Daily Telegraph this weekend reports on a new expert study which has raised fears that some clinics may be offering techniques that put the embryo at risk for their own profit. The review, carried out by Dr Justin McCracken, the former head of the Health Protection Agency, highlighted a new technique, known as Pre-Implantation Genetic Screening (PGS), as one which is possibly being offered inappropriately for commercial reasons
How Personality Affects Fertility: Men's and Women's Personalities Linked to Likelihood That They Will Have Children
A new study from IIASA population researchers finds a link between men's and women's personalities and the likelihood that they will have children. Men with neurotic personality traits are having fewer children compared to previous generations, according to a new study published in the European Journal of Personality. The study examined the effect of personality on how likely a person is to have children, using extensive survey and birth registry
Survey: only 13% of Catholics think IVF is morally wrong
Only 13% of Catholics-and 12% of Americans-believe that in vitro fertilization is morally wrong, according to a new Pew Research survey. 33% of Americans judge the procedure morally acceptable, while 46% say that it is not a moral issue.
Informal sperm donation and introduction websites: a case for more regulation?
The recent judgment handed down in the case of M v F and H [2013] on 5 July highlights difficulties with regard to legal parentage in cases of informal donor situations, which are not regulated by the Human Fertilisation and Embryology Authority (HFEA).This case involved a married heterosexual woman who was unable to conceive with her husband and sought the assistance of a donor through an online 'introduction' website for donors and women or cou
Safety drive to stop IVF clinics putting profit before embryos
An expert study raised fears that some clinics may be offering techniques that put the embryo at risk for their own profit. In the future, all clinics will have to publish the number of complications suffered by their patients. The review, carried out by Dr Justin McCracken, the former head of the Health Protection Agency, was ordered to reduce the cost of regulating the fertility industry, which has grown rapidly in recent years.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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