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DNA fragmentation of human sperm can be detected by ligation-mediated real-time polymerase chain reaction
These results indicate that the LM-RT-PCR technique is another useful tool for detecting DNA fragmentation, a parameter of sperm quality in human semen alone or combined with TUNEL or SCD assays.
Studies on enhancing embryo quantity and quality by immunization against inhibin in repeatedly superovulated Holstein heifers and the associated endoc
These results also demonstrate that active immunization against inhibin, in conjunction with the conventional superovulation protocol, can constitute a new technique for consistent improvement of bovine embryo production in vivo: while passive immunization with anti-inhibin antibody can improve embryo production in vitro.
A critique of potential in vitro fertilization (IVF) strategies to prevent babies from developing a common class of genetic diseases is sparking controversy. In today’s issue of Science, three evolutionary biologists argue that the ethical and scientific debates over an experimental IVF approach called mitochondrial replacement have underplayed some potential risks of the technique. While the trio support further development of the therapy, they
Microbiota of the seminal fluid from healthy and infertile men
Diverse kinds of bacteria were present in the human semen, but there were no significant differences between sperm donors and infertility patients. The presence of Anaerococcus might be a biomarker for low sperm quality.
Influence of the zona pellucida of the mouse egg on folliculogenesis and fertility
All mammalian eggs are surrounded by a relatively thick extracellular coat, called the zona pellucida (ZP), that plays vital roles during oogenesis, fertilization, and preimplantation development. The mouse egg ZP consists of three glycoproteins, called mZP1-3, that are syn-thesized solely by oocytes during their 2-to-3 week growth phase. [Download PDF free]
Assisted hatching of fertilised eggs to improve the chances of pregnancy in assisted conception (IVF and ICSI)
Assisted hatching is a technique sometimes used for IVF (in vitro fertilisation) and similar procedures. It involves thinning the coat surrounding the fertilised egg, or making a hole in it. It is suggested that this may improve the chance of the embryo attaching to the womb so that pregnancy can begin. In this review of randomised controlled trials there was no evidence of a benefit in the live birth rate with assisted hatching although there wa
Prenatal exposure to certain chemicals has been documented to increase the risk of cancer in childhood: adult male exposure to pesticides is linked to altered semen quality, sterility, and prostate cancer: and postnatal exposure to some pesticides can interfere with all developmental stages of reproductive function in adult females, including puberty, menstruation and ovulation, fertility and fecundity, and menopause.
Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization
Selective transfer of euploid embryos showed that implantation and pregnancy rates were not significantly different between reproductively younger and older patients up to age 42 years. Some patients who start an IVF cycle planning to have chromosome screening do not have euploid embryos available for transfer, a situation that increases with advancing maternal age. Mounting data suggests that the dramatic decline in IVF treatment success rates w
Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)
The goal of this research study is to compare the pregnancy rates for two different types of progesterone supplementation after in-vitro fertilization (IVF)
Association of blood type and patient characteristics with ovarian reserve
Other investigators have reported an increased risk for DOR in patients with blood type O and a protective effect on ovarian reserve for blood type A. We observed no association between a woman's blood type and DOR. We found an increased risk for DOR in patients aged 35 and older. Obesity (BMI ≥::30 vs. BMI <25) was associated with lower odds of DOR.
Houston Fertility Institute Participates In The Thrive-IVF Research Study To Help Improve Pregnancy Success Rates And Outcomes In Women With A History
Houston Fertility Institute today announced its participation in the Thrive-IVF Research Study, a Phase 2 clinical trial sponsored by Nora Therapeutics, Inc., to evaluate the efficacy, safety and tolerability of NT100 in women who have had repeated in vitro fertilization (IVF) failures despite having good quality embryos.
A Multi-Center Study To Evaluate Multiple Doses of NT100 Following IVF In Women With Repeated IVF Failures (Thrive-IVF)
The purpose of this study is to evaluate the efficacy, safety and tolerability of multiple doses of subcutaneous NT100 vs placebo following in vitro fertilization (IVF) in women with a history of repeated IVF failures.
The British babies made in India: Indian infertility clinic awaits 600th delivery
The surrogate mothers of India’s Akanksha Clinic gleefully await their 600th delivery. But what is the ethical price to pay, asks Tom Rowley. Michael and Veronica have spent months preparing a nursery for their firstborn twins. Piles of baby clothes lie across three beds — two for the babies and one for Veronica, who will lie awake with them each night. Feeding and nappy stations stand against the wall, which is covered in Winnie-the-Pooh paper.
JAIPUR: Growing infertility among couples is giving rise to number of doctors who are eager to open their own hospitals for IVF or in vitro fertilization, a treatment for infertility. At least 13 doctors from various districts have applied for opening IVF clinics in the state with an investment of at least Rs 3 crore.
Scientists warn of potential mitochondrial replacement IVF health risks
A group of scientists has expressed concerns that it may be too soon to bring mitochondrial replacement (MR) techniques, which are still under development, to the clinic. This follows the recent news that the UK Government will support the introduction of mitochondrial replacement therapy, with the relevant legislation due to be debated in Parliament next year (reported in BioNews 711).
What does real scientific work look like? As neuroscientist Stuart Firestein jokes: It looks a lot less like the scientific method and a lot more like "farting around … in the dark." In this witty talk, Firestein gets to the heart of science as it is really practiced and suggests that we should value what we don’t know - or “high-quality ignorance” - just as much as what we know.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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