Comment:Mainly mail items rather than new publications. There were two news items of interest. One was about the possibility of a patent on time-lapse imaging causing an increase in the cost of IVF and the second on uterine scratching (news item only at this stage - a bit of publicity seeking! since a publication to support their claims has not yet been recovered). Plus a disturbing article from Scientific American in Bob Edwards.
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Effects of caloric intake timing on insulin resistance and hyperandrogenism in lean women with polycystic ovary syndrome
In lean PCOS women, a high caloric intake at breakfast with reduced intake at dinner results in improved insulin sensitivity indices and reduced cytochrome P450c17α: activity, which ameliorates hyperandrogenism and improves ovulation rate. Meal timing directed at lowering insulin secretion in lean women with the PCOS could ameliorate their hyperandrogenism and increase ovulation rate.
Follicular fluid insulin like growth factor-1 (FF IGF-1) is a biochemical marker of embryo quality and implantation rates in in vitro fertilization cy
FF IGF-1 is a plausible biochemical marker of embryo quality and implantation rate and correlates with clinical pregnancy rates in conventional IVF cycles.
Refuting a misguided campaign against the goal of single-embryo transfer and singleton birth in assisted reproduction
While a healthy singleton birth is widely considered to be the ideal outcome of such treatment, a vocal minority continues a campaign to advocate the benefits of multiple embryo transfer as treatment and twin pregnancy as outcome for most ART patients.
Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice
Personalized IVF offers several benefits: it enables clinicians to give women more accurate information on their prognosis thus facilitating counselling especially in cases of extremes of ovarian response. The deployment of therapeutic strategies based on selective use of GnRH analogues and the fine tuning of the gonadotrophin dose on the basis of potential ovarian response in every single woman can allow for a safer and more effective IVF practi
Fertility treatment and childhood cancer risk: a systematic meta-analysis
The results of the largest meta-analysis on this topic to date indicate an association between fertility treatment and cancer in offspring. However, our results do not rule out that factors related to underlying subfertility, rather than the procedure itself, are the most important predisposing factors for childhood cancer.
Age thresholds for changes in semen parameters in men
Our findings project a declining likelihood of pregnancy following intercourse with men >34 years old, independent from the woman’s age and increasing with advancing age. Age-related mechanisms associated with this oligoasthenoteratozoospermic progression are discussed.
Fertility Problems? Joining the 'Breakfast Club' Can Help
Another finding showed that among the "breakfast" group, testosterone (one of the androgens) levels decreased by nearly 50%, while the "dinner" group level stayed neutral. In addition, there was a much higher rate of ovulating woman within the "breakfast group" compared to the "dinner" group, showing that eating a hearty breakfast leads to an increase in the level of fertility among woman with Polycystic Ovary Syndrome.
Commentary: The Eugenics Legacy of the Nobelist Who Fathered IVF
Edwards’s passing earlier this year prompted an outpouring of praise. He has been widely described as a maverick researcher disinterested in personal recognition who simply wanted to give babies to those who couldn’t make them on their own. [Ed Note: this link has been posted only because it appears in a populist scientific magazine-IVFDaily does not support these views]
Scientists say a technique called "endometrial scratching" can improve the live birth rate for women by around 20%. Scientists in Nottingham and Brazil claim the technique called "endometrial scratching" has improved the live birth rate by around 20%. It involves medically administering damage to the inner lining of the womb. While it is not a new procedure, the study looks into the optimal timing for giving the procedure to a patient, shortly be
Last week, a woman who suffered an early menopause gave birth. We report on the new frontiers of making babies. Even the late Prof Sir Robert Edwards, godfather of assisted reproduction, would be astonished by the experimental treatments that today’s fertility scientists keep coming up with.
IVF mix-up: Medical centre not liable for child's upkeep
The High Court has rejected a bid by the mother of a baby born from an in-vitro fertilisation (IVF) mix-up to get those responsible to pay for raising the child.
Assistant Registrar David Lee, while admitting that this was "a thorny issue that has plagued" the courts, ruled that as a matter of public policy, the birth of a healthy child cannot be the subject of damages. But he made it clear that the defendants will not go "scot-free" if they a
The young couple inspecting Dr Bassem Elhelw’s Cairo Fertility Clinic knew what they wanted from him: a baby boy. They also knew they wanted the child by in vitro fertilisation (IVF).After only four months of marriage they were already experienced at this game. They had seen two other fertility doctors, and the young woman had undergone two ovulation inductions to stimulate egg development.
Researchers voice 'extreme concern' as deadline to challenge patent for time-lapsed microscopy looms.Scientists have only a few weeks to block a patent that could have serious implications for couples seeking IVF treatments in Europe. This is the stark warning from researchers writing in the journal Reproductive BioMedicine Online.
Genepeeks firm to offer 'digital baby' screen for sperm donors
A service that digitally weaves together the DNA of prospective parents to check for potential disease in thousands of "virtual babies" is set to launch in the US by December. New York start-up Genepeeks will initially focus on donor sperm, simulating before pregnancy how the genetic sequence of a female client might combine with those of different males.
Mom's Weight Gain During Pregnancy Tied to Childhood Obesity
A study of 41,133 mothers and their children in Arkansas has shown that high pregnancy weight gain increases the risk of obesity in those children through age 12. The findings, published Oct. 1 in PLoS Medicine, suggest pregnancy may be an especially important time to prevent obesity in the next generation.
India's surrogacy tourism: exploitation or empowerment?
In a globalised world where everything at home is becoming more costly, outsourcing your needs to a third party thousands of miles away for less money makes a lot of sense. For a country like India, one of the top global destinations for outsourcing, the benefits are tremendous – creating millions of jobs in sectors ranging from garment, software and car manufacturing to call centres and back office operations.
Wealthy Chinese seek U.S. surrogates for 2nd child, green card
Wealthy Chinese are hiring American women to serve as surrogates for their children, creating a small but growing business in $120,000 "designer" American babies for China's elite. Surrogacy agencies in China and the United States are catering to wealthy Chinese who want a baby outside the country's restrictive family planning policies, who are unable to conceive themselves, or who are seeking U.S. citizenship for their children.
Shady Grove Fertility Launches New Shared Risk 100% Refund Guarantee for Patients Using Frozen Embryos.
Shady Grove Fertility is expanding their signature financial service, the Shared Risk Program, to now include Frozen Embryo Transfers (FET). Shady Grove Fertility has several financial programs to help reduce the cost of FET cycles: however, now that SGF has launched the Shared Risk 100% Refund Guarantee for FETs, patients gain the same piece of mind that thousands have had with the traditional Shared Risk 100% Refund for IVF or Donor Egg Program
A "hugely ethically controversial" decision allowing an American company to patent technology which could allow the creation of "designer" babies has been criticised by ethicists. - - US authorities issued a patent for a "family traits inheritance calculator", which can predict from a saliva sample aspects of a baby's appearance and risk of certain diseases, to the genetics company 23andMe last week.
IVF babies 'are a third more likely to develop childhood cancer'
Children born as a result of IVF are a third more likely to get cancer, a major study found. Scientists said those born after fertility treatments were 33 per cent more likely to have childhood cancer. They were 65 per cent more likely to develop leukaemia and 88 per cent more likely to develop cancers of the brain and central nervous system.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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