Comment:A link to a news story from Spain where the music played during embryo culture was purported to be beneficial. We need serious studies on this because we all play music during ICSI. What if the music choice of the embryologist was influencing the music tastes of IVF children. PLus some links on a new Diff-Quik Sperm DNA test and stories about the commercialisation of Australian IVF. PLUS a summary of the changing trends in oocyte donation from the USA.
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Does Krugers strict criteria have prognostic value in predicting ICSI clinical results?
There was no statistically significant difference between regarding groups regarding the rates of fertilization, implantation, clinical pregnancy, biochemical pregnancy, abortion, and live birth. The authors concluded that the normal sperm morphology defined by Krugers strict criteria and sperm motility will not be able to predict prognosis of ICSI cycles.
Outcomes of Donor Oocyte Cycles in Assisted Reproduction
Given the promising data presented by Kawwass et al8 on perinatal outcomes after use of donor oocytes, the use of oocyte donors is likely to at least remain constant and may even increase. More complete data on both short- and long-term outcomes of donation are needed so donors can make truly informed choices and, once those data are available, mechanisms can be put in place to ensure that the donor recruitment and consent process at clinics is c
Trends and Outcomes for Donor Oocyte Cycles in the United States, 2000-2010
In the United States from 2000 to 2010, there was an increase in number of donor oocyte cycles, accompanied by an increase in good outcomes. Further studies are needed to understand the mechanisms underlying the factors associated with less successful outcomes.
Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following
In conclusion, the Diff-Quik staining assay provides useful information regarding ART success, particularly in IVF cycles, where some degree of ‘natural’ sperm selection may occur: but not in ICSI, where sperm selection is operator dependent. This quick and low-cost assay is suggested as an alternative method to detect sperm chromatin status in minimal clinical settings, when no other well-established and robust assays (e.g. Sperm chromatin stru
Elimination of apoptotic spermatozoa by magnetic-activated cell sorting improves the fertilization rate of couples treated with ICSI procedure
Couples with unexplained infertility (UI) tend to have low fertilization rates using current in vitro fertilization procedures. The aim of this study was to evaluate whether elimination of apoptotic spermatozoa could increase the likelihood of pregnancy by intra-cytoplasmic sperm injection (ICSI). - These results demonstrate that non-apoptotic spermatozoa display higher fertilization potential and embryo quality following ICSI.
Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study.
Conclusions: Within the limitations of a retrospective study (albeit with a remarkably large number of observations), our results suggest that transvaginal ultrasound-diagnosed adenomyosis could have a negative impact on the main IVF/ICSI outcomes. Improving the diagnostic validity and scoring of disease severity in patients with adenomyosis is suggested.
Adenomyosis reduces pregnancy rates in infertile women undergoing IVF
The clinical pregnancy rate (22.2% versus 47.2%) and ongoing pregnancy rate (11.1% versus 45.9%) were significantly lower in women with adenomyosis and the miscarriage rate (50.0% versus 2.8%) was significantly higher in women with adenomyosis (all P<0.001). Ultrasound evidence of adenomyosis is found in a significant number of women presenting with infertility and has a negative impact on the outcome of IVF/ICSI.
This objective and reliable data should also be useful to reduce multiple pregnancies, because of the possible complications involved, transferring only one embryo. This review details what is known about time-lapse imaging, providing an overview of the advantages and applications of this technology as well as going through some of the most relevant studies published in this field.
Defective oocytes are not a common cause of unexplained infertility as determined by evaluation of sharing oocytes between infertile donors and recipi
Abnormal embryos resulting from an oocyte or sperm defect do not appear to be a common cause of unexplained infertility. The possibility does exist that sperm may be an etiologic factor in reduced fertilization potential, which not only could be obviated by conventional oocyte insemination, but could be further improved by intracytoplasmic sperm injection (ICSI).
Big money, some claim, has muddied the waters of IVF, and placed profits before people. By Julia Medew and Mark Baker.
Read more: http://www.smh.com.au/national/health/making-babies-20131014-2vhbk.html#ixzz2iJSWYtIM
US: New IVF procedure helps lesbian couples become parents
An increasing amount of female same-sex couples are undergoing a new IVF procedure which allows both women to share the biological role when having a child. This “two-mom” approach involves one woman’s eggs being mixed in a lab dish with donated sperm and then implanted into the other woman, who carries the pregnancy.
The cost of some IVF services has soared as private equity funds have moved in on many Australian clinics looking to profit from the booming business of infertility. Patient bills seen by Fairfax Media reveal the cost of a single fresh IVF cycle at Melbourne IVF before Medicare rebates or private health insurance are applied has increased from about $3833 in 2007 to $8640 in 2012 – an average increase of 18 per cent per year.
Infertility Problems? Eating Tips to Boost Fertility
Women who watch their weight and closely follow a Mediterranean-style diet high in vegetables, vegetable oils, fish and beans may increase their chance of becoming pregnant, according to dietitians at Loyola University Health System (LUHS).
Chlamydia epidemic may cause rise in infertility among young Australians, experts warn
Health experts are warning that an epidemic of chlamydia may herald a wave of infertility among young Australians. Last year, nearly 83,000 Australians under age 24 tested positive for the common sexually transmitted infection.
Increase Seen in Donor Eggs for in Vitro Fertilization, Improved Outcomes
Between 2000 and 2010 in the United States the number of donor eggs used for in vitro fertilization increased, and outcomes for births from those donor eggs improved, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the American Society for Reproductive Medicine and the International Federation of Fertility Societies joint annual meeting.
Meet Freddie, the first British baby born thanks to Nirvana, Madonna and Metallica being played in his IVF lab
Meet Freddie, the first British baby to be born thanks to music-assisted fertility treatment. His proud parents had suffered the heartache of two miscarriages and a failed attempt at IVF before hearing about the innovative technique in which music is played to eggs in a dish. Studies suggest that the tiny vibrations produced by music give fertilisation a helping hand. [Ed: I am not sure I would publicise this - we all play music during ICSI!]
Research presented at the International Federation of Fertility Societies/American Society for Reproductive Medicine meeting showed that finances were a leading concern of patients undergoing In Vitro Fertilization (IVF) procedures.
NEWSLETTER - INTERNATIONAL FEDERATION OF FERTILITY SOCIETIES AUTUMN 2013
Two articles on Human Reproductive Capacity and Environmental Exposures AND Birth Defects in Children Born Following Assisted Reproduction worth reading [ed]
International Federation of Fertility Societies (IFFS)
Founded in 1951, the mission of the International Federation of Fertility Societies (IFFS) is to stimulate basic and clinical research, disseminate education, and encourage superior clinical care of patients in infertility and reproductive medicine worldwide. As part of its educational outreach, each year IFFS conducts workshops in selected cities in underdeveloped countries, sponsors a Symposium in its International Series on topics of region
'Mini-IVF,' using fewer drugs, sees greater success in women over 35
A new form of in-vitro fertilization requiring a low dose of the drug Clomid over a longer period has shown better results than conventional IVF in women over 35 and women over 40, the doctor who developed the treatment said.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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