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Analysis of clinical outcomes with respect to spermatozoan origin after artificial oocyte activation with a calcium ionophore
A total of 185 ICSI cycles with a history of no or low fertilization was included in this retrospective study. The outcomes of AOA after ICSI were compared with ejaculated-normal, ejaculated-oligo-astheno-terato or extracted-testicular spermatozoa.: There were significant differences between the previous standard ICSI cycles and AOA cycles in the rate of fertilization and clinical outcomes among cases with different sperm origins. Thirty-eight he
Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method: A time-lapse study
Compared to 2PN, more 3PN IVF embryos displayed early cleavage into 3 cells (p :< :0.001), displayed longer duration of the 3-cell stage (p :< :0.001), and arrested development from the compaction stage and onwards (p :< :0.001). For the IVF embryos, the 2nd and 3rd cleavage cycles were completed within the expected time frame. However, timing of the cell divisions within the cleavage cycles differed between the two
Perceptions among infertile couples of lifestyle behaviors and in vitro fertilization (IVF) success
Patient perceptions of the impact of lifestyle factors on IVF success vary by sex, infertility diagnosis and socioeconomic factors. Despite counseling to the contrary, many patients perceive benefit to rigorous exercise during the IVF cycle and complete bedrest following transfer. Results provide insight into patient beliefs and highlight opportunities to improve patient education, alleviate patient anxieties and potentially improve IVF outcomes.
Sexual orientation of women does not affect outcome of fertility treatment with donated sperm
71.8% of heterosexuals and 69.0% of lesbians had a child after treatment./For D-IUI, the live birth rate was 12.8% for heterosexuals and 16.0% for lesbians and the live birth rate for all IVF embryo transfers (fresh and thawed cycles) was 28.7% for heterosexuals and 26.2% for lesbians.
The prevalence of polycystic ovary syndrome in a normal population according to the Rotterdam criteria versus revised criteria including anti-Mülleria
AMH may be used as a marker of polycystic ovaries in PCOS. However, future studies are needed to validate AMH threshold levels, and AMH Z-score may be appropriate to adjust for the age-related decline in the AFC.
Addressing the particular recordkeeping needs of infertile orthodox Jewish couples considering the use of donated eggs
Infertility counseling is a specialized field that will continue to grow in coming years as the impact of infertility and its treatment is documented more and more in terms of emotional, physical, social and life consequences. Counselors should anticipate issues that may arise in the future and assist couples in their efforts to address them. We report here on recordkeeping issues of possible future concern that should be addressed when Orthodox
The CatSper calcium channel in human sperm: relation with motility and involvement in progesterone-induced acrosome reaction
CatSper1 protein was localized in the tail of human sperm/ CatSperI expression was higher in swim up selected than unselected sperm/ A positive correlation was found between CatSper1 protein expression and the percentage of sperm with progressive motility (n = 19, r = 0.59, P = 0.007)/ Overall, our results indicate that, in human sperm, CatSper channel expression and function are associated with progressive motility and may be involved in the pa
Beyond the dichotomy: a tool for distinguishing between experimental, innovative and established treatment†
The scoring tool reflects the continuous progression of a new procedure from experimental through innovative to established. For this evolution, four criteria were considered relevant. The first (efficacy) is a categorical criterion (pass/fail). The other three criteria (safety, procedural reliability and transparency and effectiveness) are ordinal in nature. Thresholds have been introduced for all four criteria to avoid that a technology scorin
Anti-Müllerian hormone is a more accurate predictor of individual time to menopause than mother's age at menopause
This study shows that AMH is a more accurate predictor of ANM than mother's ANM. However, before achieving clinical applicability, the certainty with which a woman's prediction is made must improve. The association between mother's ANM and TTM in daughters did not appear to be influenced by whether ANM was recorded by mothers or daughters—an important finding because in the clinical setting daughters usually provide this information.
The physiology and clinical utility of anti-Müllerian hormone in women
For the first time in female reproductive biology, it is possible to measure the submerged part of the iceberg of follicle growth, i.e. the intrinsic, so-called ‘acyclic’ ovarian activity. An international standard for AMH and improved assay validity are urgently needed to maximize the clinical utility of this very promising biomarker of ovarian function in a large array of clinical situations, both in childhood and adulthood.
Obesity in Mothers Alters Babies Weight Through Brain Rewiring
Obese mothers are more likely to have children with metabolic disorders such as diabetes compared with thin mothers, but the underlying molecular and cellular reasons for this effect have been unclear. A study published by Cell Press on January 23rd in the journal Cell reveals that the offspring of mouse mothers on a high-fat diet are predisposed to obesity and diabetes because of abnormal neuronal circuits in the hypothalamus - a key brain regio
Embryo 'adoption': Clinic seeks to match unused IVF embryos with loving families
“[Using a sperm or egg donor] seemed like going outside of our marriage,” Hawkins, now 33, told FoxNews.com. “So we decided [a baby] will either be from both of us or…we’ll go the route of adoption.” But instead of a traditional adoption, the couple decided to pursue another option: embryo donation – also sometimes referred to as embryo “adoption.”
“IVF births carry five times risk of complications,” the Daily Mail reports. While this headline is essentially true, it is a classic example of a “relative risk” which sounds frightening out of context. In this case, the headline ignores the fact that the number of serious complications found, such as stillbirth and neonatal death was very small.
How 73% of health trusts won't fund full IVF: Thousands of women being denied treatment because of rules to save money.
Thousands of women are being denied fertility treatment because health trusts are imposing ‘unfair’ rules to save money, a report warns today.
Six have stopped paying for IVF altogether. Three quarters are refusing to offer women at least three courses of treatment, as set out in official guidelines, because it is too expensive. Most will not fund treatments for women if their partners smoke, are obese, drink too much or have children from a pre
LACK OF REGULATION: MUSHROOMING IVF CLINICS ACROSS INDIA
In value terms, India’s IVF market is anticipated to have touched the mark of INR 14.2 Billion by the end of 2013. The very market is anticipated to register a double digit CAGR over the 5 year period spanning from 2013 to 2018. In the coming years, many new IVF clinics are likely to start operating in India. Furthermore, on the technological front, some novel and advanced technologies are also under development, which will find substantial use i
How Iran became a leader in fertility treatment, courtesy of the Ayatollahs
Yet, there is one area in which the country has shown a progressive bent: fertility treatment. Iran is actually a leader in the field of fertility treatment — attracting couples looking for in vitro fertilization, or IVF, from all over the Middle East. And it's all due to support from the Ayatollahs. Demand for IVF is high in Iran, in part because more women are waiting to get married and have families until they're in their 30s and 40s, said Aza
IVFAustralia has announced they are an official supporter of Sydney Gay and Lesbian Mardi Gras 2014, and presenting partner of Women Say Something.
In a media statement released today, the group says in the past twelve months the number of same-sex couples seeking their assistance for reproduction has increased to 36 percent and it makes sense to raise awareness of IVF and encourage gay men to become donors by supporting Mardi Gras. [ed should
Proudly cuddling her twin brother, the sister who is eight years older: Siblings were conceived at the same time using IVF before embryo was frozen.
These are the amazing twins who were born EIGHT years apart.
Jasmine and Simon Billington were conceived at the same time with sperm that was frozen but Jasmine was born in May 2005 and her ‘twin’ brother was born in May last year. [Ed When you think about this, epidemiologists may need to know when children were conceived not born for some studies]
In 2012, 16,748 IVF treatments carried out and there are about 4,700 babies born. Thus, 2012 is a little less than 2011 IVF year./However, the number of multiple pregnancies from IVF decreased 293 twins and triplets 5, which is less than a year earlier. 1 in 8 multiple births conceived in 2012, are conceived using IVF. 1 in 37 children in the year 2012, his IVF children.
Several infertility clinics in Hyderabad found flouting ICMR guidelines
Many infertility clinics in Hyderabad are found flouting Indian Council of Medical Research (ICMR) guidelines because of which many clinics are witnessing low success rate in the state. According to sources, many infertility clinics in the twin cities of Hyderabad and Secunderabad in Andhra Pradesh are not maintaining documentation of cases and all the equipment used for the commission of in vitro fertilization (IVF) babies are not of high qualit
Evaluation of Cleavage by time lapse Imagery
[This link may be from a sponsor]
Comment = Evaluation of Cleavage by time lapse Imagery. The module uses videos from EmbryoScope as supplied by IVFA. When complete, there will be 12 releases, one per month in 2014. Each will show one video of the complete cleavage stages of a single human embryo. Participants will be as to assess the time to reach critical stages and to grade the final blastocyst.
Embryo Video Ranking: New for 2014. Developed for users of Time-lapse Embryo grading. [This link may be from a sponsor]
Comment = The release show videos of 4 embryos as visualised using an EmbryoScope unit. You are asked to rank these from best (1st) to least good (4th). Based upon the replies received, your ranking is calculated upon whether your selections agree with the majority of the other replies.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
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