Comment:This mail contains some links to the Journal of clinical investigations with some recent review articles that may be of interest to new scientists.
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DNA integrity, growth pattern, spindle formation, chromosomal constitution and imprinting patterns o
DNA breaks appear to be rapidly repaired and vitrification of oocytes inside pre-antral follicles by the Cryo-Top method does not appear to increase risks of abnormal imprinting or disturbances in spindle formation and chromosome segregation.
Review Series The key role of vitamin A in spermatogenesis
Spermatogenesis in adult mammals is highly organized, with the goal being continual sperm production. Vertebrate testes are arranged into recurring cellular associations that vary with time and distance along the tubule. These changes over time and d
Review Series Fertilization: a sperm`s journey to and interaction with the oocyte
Mammalian fertilization comprises sperm migration through the female reproductive tract, biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct. Recent gene knockout approaches in mice have revealed that many factors
Review Series Making the blastocyst: lessons from the mouse
Mammalian preimplantation development, which is the period extending from fertilization to implantation, results in the formation of a blastocyst with three distinct cell lineages. Only one of these lineages, the epiblast, contributes to the embryo i
Review Series The ovary: basic biology and clinical implications
The classical view of ovarian follicle development is that it is regulated by the hypothalamic-pituitary-ovarian axis, in which gonadotropin-releasing hormone (GnRH) controls the release of the gonadotropic hormones follicle-stimulating hormone (FSH)
Review Series Portrait of an oocyte: our obscure origin
Oocytes play a pivotal role in the cycle of human life. As we discuss here, after emerging from germline stem cells in the fetus, they grow in a follicular niche in which development is harmonized for timely ovulation and hormone secretion after pube
Researchers unlock DNA clues to debilitating womens disease endometriosis
Professor Montgomery said that studying how the DNA variations affected the expression of surrounding genes would help scientists better understand the causes of endometriosis, which affects up to 10 per cent of women of reproductive age.
Feasibility of Repurposing the Polyanionic Microbicide, PPCM, for Prophylaxis against HIV Transmissi
HIV-serodiscordant couples wishing to conceive often seek assisted reproduction, during which spermatozoa from infected men are washed to minimize the risk of HIV transmission to partner and fetus. We sought to improve this method by adding a microbi
Scientists say they are one step closer to solving one of the mysteries of human sexual development. Scientists at the University of Adelaide have found an ancient brain gene responsible for tricking foetuses into forming male sex organs without a Y
US scientists have used stem cell technology to create mice from two fathers, an advance that they say could help preserve endangered species and even help same-sex couples have their own genetic children one day.
Men with type 1 diabetes may one day be able to use stem cells from their testicles to replace their damaged insulin-secreting beta islet cells, say US scientists.
Ten percent of American couples trying to conceive are affected by infertility. Genetic and environmental factors, medical treatments, such as chemotherapy and radiation, as well as unknown triggers all can lead to infertility. With treatment options
IN 21st-century Australia, the typical family who arrives at the complicated crossroads of commercial surrogacy is afraid and demoralised. While many commentators would have us think they are a gay couple wanting a designer baby, they are more likel
BBC News - Oestrogen may fuel oral cancer in young women
The hormone oestrogen could be fuelling head and neck cancers in young women, explaining why the disease is on the increase in that group, a US team says. Writing in Cancer Prevention Research, they said oestrogen helped pre-cancerous cells move and
A Melbourne couple is trying to win the legal right to select the gender of their next child. Victoria's medical legal body, the Patient Review Panel, recently rejected the couple's application to choose to have a baby girl through IVF.
IVF breakthrough `will increase chance of pregnancy`
South Australian researchers say a breakthrough in IVF technology will increase the chances of women becoming pregnant. The researchers at the University of Adelaide have developed a product that improves the rate of embryo implantation by up to 40
A CONTRACEPTIVE device fitted in women's arms has misfired, with more than 400 Australian users becoming pregnant. And women in Britain have received thousands of pounds in compensation for unwanted pregnancies.
EQA scheme for Follicular AMH [This link may be from a sponsor]
An EQA scheme to estimate the Follicular Phase Serum AntiMullarian Hormone concentration. Ten samples to be analysed between February and November 2011 containing 0.8-1.0 ml serum from multiple women during the follicular phase of IVF treatment. The
Requirements for the Supervision of Pathology Laboratories-Proposed Changes
This page contains draft documents currently under consideration by the National Pathology Accreditation Advisory Council (NPAAC) which is managed by the Australian Government Department of Health and Ageing. If you wish to submit a response to the d
Requirements for Pathology Laboratories This is a Tier 2 NPAAC document that determines the minimum standards acceptable for good pathology laboratory practice in Australia. It addresses a variety of issues such as: laboratory ethics, quality system
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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