Comment:This digest starts with Bionews articles on UK iVF issues, links to aneuploidy rates in blastocysts, to the impact of stress on IVF and ends with articles on James Brown, an Australian pioneer in reproductive endocrinology.
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Prof. Brown's work revolutionized reproductive medicine by permitting accurate monitoring of ovarian activity before the days of pelvic ultrasound and led to safe and effective monitoring for ovulation induction, IVF and prediction of spontaneous ovu
Types of ovarian activity in women and their significance: the continuum (a reinterpretation of earl
CONCLUSIONS The findings explain the erratic fertility of women and why ovulation is not always associated with fertility. They provide an understanding of the various types of ovarian activity and their relation to pituitary function, fertility and
The purpose of this review is to open a debate as to whether or not oocytes actively repel supernumerary sperm or in nature final sperm : oocyte ratios are so low that polyspermy preventing mechanisms are not necessary. Before encountering the oocyte
Is sperm DNA damage associated with IVF embryo quality? A systematic review
Conclusions This systematic review indicates that the evaluable studies are heterogeneous and that overall, there is no consistent relationship between sperm DNA damage and embryo quality and/or development. The data also suggest that the influence
Emotional distress in infertile women and failure of assisted reproductive technologies: meta-analys
Conclusions The findings of this meta-analysis should reassure women and doctors that emotional distress caused by fertility problems or other life events co-occurring with treatment will not compromise the chance of becoming pregnant.
The current WHO criteria for semen quality do not discriminate between fertile and subfertile men. Our redefined and graded semen criteria have strong predictive value. If interpreted correctly, the fast and inexpensive semen analysis remains the gol
Morphological nuclear integrity of sperm cells is associated with preimplantation genetic aneuploidy
Spermatozoa free of nuclear morphological malformations were found to be significantly associated with the lower incidence of aneuploidy in derived embryos, resulting in lower rates of cycle cancellation.
Ovarian stimulation and the risk of aneuploid conceptions
The incidence of embryonic aneuploidy was not higher in pregnancies conceived with FSH stimulation compared with spontaneous conceptions in infertility patients. This suggests that exogenous FSH exposure does not increase the risk of aneuploidy
A comparison of the effects of three different luteal phase support protocols on in vitro fertilizat
In assisted reproductive technology cycles including treatment with GnRH agonist, adding 4 mg of oral E2 to P during the luteal phase significantly increased the pregnancy and implantation rates and decreased the miscarriage rate compared with the us
Oxidative parameters of embryo culture media may predict treatment outcome in in vitro fertilization
The oxidative status of the early embryo in IVF is associated with the chances of implantation. Assessment of the oxidative status of embryos in culture media before transfer may serve as an applicable tool for improving embryo selection in light of
Ultrastructural evaluation of human metaphase II oocytes after vitrification: closed versus open dev
Conclusion(s) These preliminary data suggest that oocyte ultrastructure is better preserved with an open rather than closed vitrification and warming protocol.
BioNews - Birth of surrogate child highlights difficulties with Indian surrogacy laws
Uncertainty has arisen over the procedures followed by an Indian surrogacy clinic following the birth of twins to a gay couple from Spain. The couple used a donated egg, which was then artificially fertilised and implanted in a surrogate. The clinic'
Influence of embryo sex on development to the blastocyst stage and euploidy
Conclusion(s) Our data suggest that extending embryo culture to day 5 does not lead to sex selection and that euploidy and aneuploidy are not sex dependent.
A bone cell hormone can regulate male fertility hormone testosterone, a study on mice has found. Male mice engineered to produce little osteocalcin, a hormone released by bone cells called osteoblasts, had smaller litters and testes than unmodified m
BioNews - Liverpool hospital to investigate `sex selection` claims
A Liverpool hospital has said it will investigate allegations that one of its doctors had apparently offered to make arrangements for an undercover reporter posing as a prospective patient to undergo a sex selection procedure for family balancing abr
It all starts with a few private minutes in a clinical room, a box of tissues and probably a men's magazine. The Senate is looking into the rights of sperm donors and the children they create.
Uterine fibroids - Health Report - 28 February 2011
While these tumours are rarely harmful, they can make life miserable for some women who experience heavy periods, clotting, anaemia and pressure on their organs.
Nicole Kidman challenges surrogacy stigma | The Australian
WE tend to hear about surrogacy arrangements only when celebrities are involved. Robert De Niro, gay pop singer Ricky Martin, 26-year-old Portuguese soccer star Cristiano Ronaldo, Elton John and David Furness have all used surrogate mums.
BBC News - Fertility treatment success is not prevented by stress
Emotional distress does not affect the success of IVF or other assisted reproductive techniques, according to a study. The report, published in the British Medical Journal aims to dispel the myth that stress prevents women from becoming pregnant.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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