Comment:Asprin,fertilisation, and a few great links to videos from a recent ISGE meeting last year on POF. Great educational value. Also when is a sperm donor not the sperm donor - find the links and read on.
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Experts grow mouse sperm to help with human infertility
Researchers in Japan used embryonic stem cells to grow healthy mouse sperm on laboratory dishes, a development which could help treat human infertility.
Cryopreservation: a cold look at technology for fertility preservation
Roger Gosden,
Cryopreservation has become a mainstay in the assisted reproduction laboratory and underpins fertility preservation for patients with cancer and other conditions. The practice is currently evolving from slow freezing methods toward more vitrification
The principal variables of cryopreservation: solutions, temperatures, and rate changes. S.P. Leibo,
When oocytes and embryos are to be cryopreserved, they are suspended in a solution of one of several low-molecular-weight solutes. The permeability of oocytes and embryos to these various low-molecular-weight compounds differs. These differences dete
Clinical application of oocyte vitrification: a systematic review of randomized controlled trials
Five eligible studies were finally included. They involved 4,282 vitrified oocytes, 3,524 fresh oocytes, and 361 slow-frozen oocytes between 2005 and 2009. The rates of ongoing pregnancy, top-quality embryo, embryo cleavage, and fertilization did not
Egg freezing for age-related fertility decline: preventive medicine or a further medicalization of r
In December 2009, the Israel National Bioethics Council (INBC) issued recommendations permitting egg freezing to prevent both disease- and age-related fertility decline. The INBC report forms the basis of Israel’s new policy regarding egg freezing.
Universal cervical-length screening and vaginal progesterone prevents early preterm births, reduces
The authors demonstrate that, by screening all singleton pregnancies, a group of women at high risk for spontaneous PTB can be identified in the middle trimester by transvaginal measurement of the cervix and that gestation can be prolonged and neonat
Prevalence of uterine anomalies and their impact on early pregnancy in women conceiving after assist
Women who are referred for ART have a high prevalence of congenital uterine anomalies, the most common anomaly being an arcuate uterus. These anomalies are not associated with a reduction in pregnancy rates following ART.
Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida
Human fertilization begins when spermatozoa bind to the extracellular matrix coating of the oocyte, known as the zona pellucida (ZP). One spermatozoan then penetrates this matrix and fuses with the egg cell, generating a zygote. Although carbohydrate
The development of copulation in the natural world [Radio Link]
John Long describes a Placoderm, a fossil fish from Western Australia that has been dated to 365 million years. The fish contained an embryo. This signalled the fish reproduced by copulation and is the earliest example known.
Elevated Non-Esterified Fatty Acid Concentrations during Bovine Oocyte Maturation Compromise Early E
These data indicate that exposure of maturing oocytes to elevated NEFA concentrations has a negative impact on fertility not only through a reduction in oocyte developmental capacity but through compromised early embryo quality, viability and metabo
Twinning propensity and offspring in utero growth covary in rural African women
In humans and other mammals, some females are more likely to experience twin pregnancies than others, but the reasons behind such individual variation are poorly understood.
Noninvasive Fetal Sex Determination Using Cell-Free Fetal DNA-A Systematic Review and Meta-analysis
Conclusions Despite interstudy variability, performance was high using maternal blood. Sensitivity and specificity for detection of Y chromosome sequences was greatest using RTQ-PCR after 20 weeks' gestation. Tests using urine and tests performed be
Researchers in Canada Call for Policy to Mandate Single-Embryo Transfer in IVF
During the 2-year period, 17% of all NICU admissions—82 infants from 44 multiple gestations—resulted from some form of assisted reproductive technology. Of the 82, 75 were twins or triplets whose mothers used IVF to become pregnant.
Prenatal and Postpartum Depression in Fathers and Its Association With Maternal Depression-A Meta-an
Conclusions Prenatal and postpartum depression was evident in about 10% of men in the reviewed studies and was relatively higher in the 3- to 6-month postpartum period. Paternal depression also showed a moderate positive correlation with maternal dep
IVF mistakes treble in Britain in the past three years
Call for more transparency in the fertility
The number of mistakes in IVF treatment has more than trebled in the UK over the past three years, figures revealed. Errors that include the loss of embryos and sperm rose from 182 cases, between April 2007 and March 2008, to 564, between April 2010
Parents-to-be wanting to find out their baby's gender can be assured that a blood test on the mother gives an accurate result, say scientists. The tests, which look for foetal DNA in the mother's blood, are sold privately in many countries, including
Maternal Fat Has Negative Impact On Embryo Development
Exposing eggs to high levels of saturated fatty acids - as commonly found in the ovaries of obese women and those with Type II diabetes - compromises the development of the embryo, according to new research published in PLoS ONE.
Research from the University of Adelaide has shown that the loss of a twin during early pregnancy explains the increased risk of birth defects in multiple IVF pregnancies.
Single babies born to mothers of twins tend to be heavier, report scientists.
The report in the journal Biology Letters is based on a 40-year data set collected in The Gambia.
Antibody Discovered That May Help Detect Ovarian Cancer in Earliest Stages
Using a new approach to developing biomarkers for the very early detection of ovarian cancer, researchers at Rush University Medical Center have identified a molecule in the bloodstream of infertile women that could one day be used to screen for thos
A Sydney man says he is devastated that his name has been taken off a 10-year-old girl's birth certificate, after a legal challenge by the mother's former lesbian partner. The girl was born in 2001 after the man, who for legal reasons can only be kno
How Sticky Egg Captures Sperm: Discovery Could Help Explain Infertility Causes and Provide New Contr
Researchers have uncovered exactly how a human egg captures an incoming sperm to begin the fertilisation process, in a new study published this week in the journal Science.
A Sydney court has ruled that a sperm donor who considers himself the father of a ten-year-old-girl should have his name stripped from her birth certificate.
Giving up smoking as soon as pregnancy is confirmed averts the adverse birth outcomes associated wit
the researchers found that those babies whose mothers had stopped smoking in the periconceptional period – around the time of getting pregnant or as soon as the pregnancy was confirmed – had a significantly higher birthweight.
Guardia™ Access Embryo Transfer Catheter with Internal Support Cannula
Used to place in vitro fertilized (IVF) embryos into the uterine cavity.
Internal support cannula enhances flexibility during embryo placement. Precurved guiding catheter facilitates in_sertion. Atraumatic bulb tip eases passage through cervix.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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Irvine Scientific
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