Comment:A bit of everything this mailout. Some recent articles in JCEM about AMH ( more to come in future distributions). NATA SIRT statement on Sperm Morphology and some interesting articles on embryology.
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Publish or perish: a maxim relevant to authors, readers and editors alike
In this issue of Reproductive BioMedicine Online, Gleicher et al. (2011) argue that the trend to apply minimal ovarian stimulation in combination with freezing all oocytes or embryos for later fertilization or transfer has been rushed into routine cl
Embryo Development Obeys the Laws of Hydrodynamics
The law of hydrodynamics can contribute to our understanding of how a cluster of embryonic cells can transform into an animal within the first 36 hours of development, according to research recently published in European Physical Journal E.
A change in boundary conditions induces a discontinuity of tissue flow in chicken embryos and the fo
The morphogenesis of vertebrate body parts remains an open question. It is not clear whether the existence of different structures, such as a head, can be addressed by fundamental laws of tissue movement and deformation, or whether they are only a se
Pretreatment Serum Anti-Müllerian Hormone Predicts Long-Term Ovarian Function and Bone Mass after Ch
Conclusion:Measurement of AMH at cancer diagnosis predicts long-term ovarian function after chemotherapy. Use of this in clinical practice may allow better prediction of chemotherapy-related risk to future fertility.
Genetic Ancestry Affects the Phenotype of Normogonadotropic Anovulatory (WHOII) Subfertility
Conclusion: Population differences add to the phenotype of normogonadotropic anovulation and need to be taken into account when evaluating the individual patient. Although effective on a continental level, the present set of ancestry markers was not
Anti-Müllerian Hormone Predicts Menopause: A Long-Term Follow-Up Study in Normoovulatory Women
Conclusions: AMH is highly predictive for timing of menopause. Using age and AMH, the age range in which menopause will subsequently occur can be individually calculated.
Postnatal Developmental Changes in the Pituitary-Ovarian Axis in Preterm and Term Infant Girls
Conclusions: The postnatal FSH surge results in transient ovarian stimulation in term and preterm girls. A delay in ovarian folliculogenesis shown in ovarian ultrasonography and by low serum AMH levels may provide an explanation for the exaggerated F
Does the Potential for Chaos Constrain the Embryonic Cell-Cycle Oscillator?
Specifically, in our simulations a fast calcium wave results in synchronized cell cycles, while a slow wave results in full-blown spatio-temporal chaos. We show that such chaos would ultimately lead to an unpredictable patchwork of cell divisions ac
CONSENSUS STATEMENT ISSUED BY SCIENTISTS IN REPRODUCTIVE TECHNOLOGY (SIRT) REGARDING THE USE OF THE
A consensus statement has been developed following the mid-year Scientists in Reproductive Technology (SIRT) Meeting held over 30 April to 1 May 2011, that the latest edition of the WHO manual should be used i.e. 5th Edition.
The need for a consensu
Oocyte cryopreservation as a fertility preservation measure for cancer patients
Advances in cancer treatment have allowed women to live longer, fuller lives. However, therapies used to treat cancer often significantly impair a woman’s future ability to have children by damaging her eggs or removing key reproductive organs. Given
Current results with slow freezing and vitrification of the human oocyte
Oocyte cryopreservation can provide a number of advantages to couples undergoing assisted reproduction or to women interested in fertility preservation. Two methods, slow freezing and vitrification, have been used successfully for oocyte cryopreserva
Theoretical and experimental basis of oocyte vitrification
This review addresses theoretical and experimental evidence accumulated over the last two decades supporting the application of vitrification and warming to oocyte cryopreservation. Issues ranging from clinical needs for oocyte cryopreservation, cryo
Reprint of: Theoretical and experimental basis of slow freezing
In human IVF, cryopreservation of oocytes has become an alternative to embryo storage. It has also shown enormous potential for oocyte donation, fertility preservation and animal biotechnology. Mouse oocytes have represented the elective model to dev
Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida
Sperm-ZP binding was largely inhibited by glycoconjugates terminated with sialyl-Lewisx sequences or by antibodies directed against this sequence. Thus, the sialyl-Lewisx sequence represents the major carbohydrate ligand for human sperm-egg binding.
Mice Prompt Look at Cholesterol's Role in Female Fertility
A small group of researchers is now wondering whether cholesterol also helps maintain fertility—and whether cholesterol abnormalities impair a woman's ability to get and stay pregnant. There's even speculation that a cholesterol-lowering drug, which
Computer-assisted embryo selection: a benefit in the evaluation of embryo quality?
Combined analysis of both scoring systems revealed that implantation was affected by number and size of blastomeres using CASS and by the degree of embryo fragmentation using SSS. Using live birth as outcome, only the number of blastomeres on day 3,
Pregnancy multivitamins - Are they essential, or just a pricey gimmick?
These days, there are specialist multi-vitamin and mineral preparations for pregnancy and breastfeeding, as well as conception. Are these supplements a gimmick, or is there good evidence they're beneficial?
Birth Control Pills Affect Memory, Researchers Find
ScienceDaily (Sep. 9, 2011) — Women who use contraceptives like birth control pills experience memory changes, according to new UC Irvine research. Their ability to remember the gist of an emotional event improves, while women not using the contracep
In the Early Life of an Embryo, a Monster Lurks: Newly Fertilized Cells Only Narrowly Avoid Degenera
ScienceDaily (Aug. 22, 2011) — Research based at Princeton University has revealed that newly fertilized cells only narrowly avoid degenerating into fatal chaos. At the same time, scientists have discovered that embryos have acquired a mechanism to c
Fatherhood 'lowers testosterone to keep men loyal'
Men appear to be biologically wired to care for their babies, say researchers who have discovered levels of testosterone go down after fatherhood.
This drop in the male hormone presumably makes the dad more family-oriented and less likely to stray
Let's retrospectively release information to Australia's donor-conceived
An Australian commercial television station recently ran a news story about a donor-conceived woman who has heritable bowel cancer (1). She did not inherit it from her mother. She is denied access to information about her sperm donor because he donat
The great delay: 33 years after the first 'test-tube' baby
July marked the 33rd birthday of the world's first 'test-tube' baby: Louise Joy Brown arrived on July 25, 1978. Since then, four million babies have been born thanks to IVF. Many more have not. The treatment does not guarantee pregnancy and the side
EQA scheme for Follicular AMH [This link may be from a sponsor]
An EQA scheme to estimate the Follicular Phase Serum AntiMullarian Hormone concentration. Ten samples to be analysed between February and November 2011 containing 0.8-1.0 ml serum from multiple women during the follicular phase of IVF treatment. The
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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