Comment:Links to new article on ICSI & freezing risks, intergenerational risk of antibiotics and an interesting article on risks!
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Reproductive Technologies and the Risk of Birth Defects
The increased risk of birth defects associated with IVF was no longer significant after adjustment for parental factors. The risk of birth defects associated with ICSI remained increased after multivariate adjustment, although the possibility of resi
Embryo collection induces transient activation of XBP1 arm of the ER stress response while embryo vi
It is important to understand the possible stresses that Assisted Reproductive Technologies place on the embryo and the mechanisms the embryo employs to adapt to these stresses. This study indicates that among the adaptive pathways available, culture
Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein
These findings reveal that ADAM3 requires testis-specific private chaperones to be folded properly and that the principle role of ADAM3 is for sperm migration into the oviduct but not for the fertilization event. Moreover, the importance of primary s
Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem C
Haploid cells are amenable for genetic analysis. Recent success in the derivation of mouse haploid embryonic stem cells (haESCs) via parthenogenesis has enabled genetic screening in mammalian cells. However, successful generation of live animals from
Questions about risk are everywhere, and in most cases science is a key player both in formulating the questions, and providing possible answers. But even though science, statistics, and bureaucratic language provide seemingly rational approaches to
A new study published today in Science Translational Medicine found, what an accompanying commentary describes as, an "unexpected and astonishing" variability over time in the vaginal bacterial communities of apparently healthy women.
Occupational exposure to formaldehyde in Chinese men may be linked to reduced fertility, reports a paper in the May Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Med
From Embryonic Stem Cells, a Sperm Replacement and Easier Path to Genetic Modification
Researchers have devised a new and improved method for producing genetically modified animals for use in scientific research. The method relies on haploid embryonic stem cells (haESCs) instead of sperm to artificially fertilize immature egg cells. S
Study Is First to Show Transgenerational Effect of Antibiotics
This study reports that male pseudoscorpions treated with the antibiotic tetracycline suffer significantly reduced sperm viability and pass this toxic effect on to their untreated sons. They suggest a similar effect could occur in humans and other sp
Insect Glands May Illuminate Human Fertilization Process
New research from Carnegie scientists focuses on secretions from glands in the reproductive tract that help sperm survive and guide the sperm on the trip to fertilize an egg. The gene that controls the development of these glands in fruit flies prov
Greater Numbers of Highly Educated Women Are Having Children, Bucking Recent History
A national study suggests that a significantly greater number of highly educated women in their late 30s and 40s are deciding to have children - a dramatic turnaround from recent history.
Gene Involved in Sperm-To-Egg Binding Is Key to Fertility in Mammals
Scientists from Durham University, UK, and Osaka University, Japan, looking at fertility in mice, have discovered for the first time that the gene, which makes a protein called PDILT, enables sperm to bind to an egg, a process essential to fertilisat
New CPD Module - Embryo Assessment by ALPHA/ESHRE guidelines [This link may be from a sponsor]
In 2011, there was a joint meeting between ALPHA and an ESHRE Special Interest Group on embryology to attempt to standardise the manner in which embryos are described. This CPD module summaries the finding from this meeting and is referenced to this
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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