Comment:Various News. QAPOnline has announced a significant discount to the 2012 QAPonline EQA scheme to promote the proficiency schemes.
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Meiosis-Specific Noncoding RNA Mediates Robust Pairing of Homologous Chromosomes in Meiosis
Pairing and recombination of homologous chromosomes are essential for ensuring reductional segregation in meiosis. However, the mechanisms by which chromosomes recognize their homologous partners are poorly understood.
Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting [RMBonline version]
This paper reports the proceedings of an international consensus meeting on oocyte and embryo morphology assessment. Following background presentations about current practice, the expert panel developed a set of consensus points to define the minimum criteria for oocyte and embryo morphology assessment. It is expected that the definition of common terminology and standardization of laboratory practice related to embryo morphology assessment will
The rate of change in Ca2+ concentration controls sperm chemotaxis
During chemotaxis and phototaxis, sperm, algae, marine zooplankton, and other microswimmers move on helical paths or drifting circles by rhythmically bending cell protrusions called motile cilia or flagella
Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients
Embryos randomized to the aCGH group implanted with greater efficiency, resulted in clinical pregnancy more often, and yielded a lower miscarriage rate than those selected without aCGH. Additional studies are needed to verify our pilot data and confirm a role for on-site, rapid aCGH for IVF patients contemplating fresh SET.
Rapid Mitochondrial DNA Segregation in Primate Preimplantation Embryos Precedes Somatic and Germline
The timing and mechanisms of mitochondrial DNA (mtDNA) segregation and transmission in mammals are poorly understood. Genetic bottleneck in female germ cells has been proposed as the main phenomenon responsible for rapid intergenerational segregation
Role of Stem Cells in Human Uterine Leiomyoma Growth
Our data suggest that LMSP, which have stem/reservoir cell characteristics, are necessary for in vivo growth of leiomyoma xenograft tumors. Lower estrogen and progesterone receptor levels in LMSP suggests an indirect paracrine effect of steroid hormo
Human spermatozoa migration in microchannels reveals boundary-following navigation
The migratory abilities of motile human spermatozoa in vivo are essential for natural fertility, but it remains a mystery what properties distinguish the tens of cells which find an egg from the millions of cells ejaculated. To reach the site of fert
A Single Stem Cell Mutation Triggers Fibroid Tumors: Mutated Stem Cell `Goes Wild` in Frenzied Tumor
Fibroid uterine tumors affect an estimated 15 million women in the United States, causing irregular bleeding, anemia, pain and infertility. Despite the high prevalence of the tumors, which occur in 60 percent of women by age 45, the molecular cause h
How Mitochondrial Genes Are Passed from Mother to Child
Research conducted at the Oregon National Primate Research Center at Oregon Health & Science University helps answer some long-standing questions about how certain disease-causing gene mutations are inherited
First study of chromosome test suggests increase in IVF success
The test – developed by the biotech company Blue Gnome – is used five days after an egg has been fertilised and helps doctors select which embryo should be implanted during fertility treatment. In a clinical trial published in the Journal of Molecula
Fertility treatment only partly responsible for increase in birth defects
The analysis, believed to be the most comprehensive of its kind, looked at the outcomes of 308,974 births in Southern Australia between 1986 and 2002, 6,163 of which used assisted reproductive techniques. They found that 8.3 percent of children born
Thirteen vials of sperm are to be divided between two women after their relationship ended, a Canadian court has ruled. It ruled the sperm should be treated as property and divided between the former couple as other joint assets were upon separation.
There have been a number of high profile cases of late involving disputes within alternative family structures. Primarily these concern fathers or known donors seeking more of a relationship with their child than they originally wished for. However,
A call by the Donor Sibling Registry to stop using the figures of 30,000 - 60,000 US sperm donor bir
Over the last twelve years, the DSR has collated the most comprehensive records that currently exist in the USA. It has records of over 1600 donors, information about tens of thousands of offspring, and details of hundreds of US sperm distribution fa
Education, Not Abortion, Reduces Maternal Mortality, Study Suggests
A scientific analysis of 50 years of maternal mortality data from Chile has found that the most important factor in reducing maternal mortality is the educational level of women.
Sperm Crawl and Collide On Way to Egg, Say Scientists
Scientists at the Universities of Birmingham and Warwick have shed new light on how sperm navigate the female reproductive tract, 'crawling' along the channel walls and swimming around corners: with frequent collisions.
Sperm Can Do `Calculus` to Calculate Calcium Dynamics and React Accordingly
Sperm have only one aim: to find the egg. The egg supports the sperm in their quest by emitting attractants. Calcium ions determine the beating pattern of the sperm tail which enables the sperm to move.
QAPonline Embryo ranking EQA [This link may be from a sponsor]
A new EQA scheme for embryologists where embryologists are graded on their capacity to rank up to 10 embryos relevant to other participants. All clinical and scientific director should enrol their staff to gauge the uniformity of the skills of their
New CPD Module - Embryo Assessment by ALPHA/ESHRE guidelines [This link may be from a sponsor]
In 2011, there was a joint meeting between ALPHA and an ESHRE Special Interest Group on embryology to attempt to standardise the manner in which embryos are described. This CPD module summaries the finding from this meeting and is referenced to this
FertAid Is Keen To Promote QAPonline To A Wider IVF Community. [This link may be from a sponsor]
To achieve this, the following 2 special offers are available.SPECIAL No 2
- 90% discount on Access to the 2012 EQA/Proficiency Schemes in Andrology, embryology and Ultrasound. Yes - A whole of clinic subscription for $AUD 250 (~E200)
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
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