Comment:IVFDaily releases a CPD module on Birth Defects and IVF. This is a module designed for nursing and scientists and completion can be used for CME/CPD points. Tell your nursing staff about it. ALSO QAPonline is now at a very low $250/year fee to encourage it widespread utilisation. TELL YOUR SCIENTIFIC DIRECTOR ABOUT THIS.
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Recombinant human phospholipase C zeta 1 induces intracellular calcium oscillations and oocyte activation in mouse and human oocytes
Repeated [Ca2+]i oscillations and oocyte activation were induced in mouse and human oocytes by microinjection of recombinant hPLCZ1 synthesized in E. Coli. Injection of recombinant protein could thus provide a biological solution for inducing artificial activation of oocytes.
Hormonal & molecular characterization of follicular fluid, cumulus cells and oocytes from pre-ovulatory follicles in stimulated and unstimulated cycle
The use of ovarian stimulation induces changes in the follicular fluid and in CC GE that may affect immune processes, meiosis and ovulation pathways. Although these differences do not seem to relate to early-stage embryo morphology, the implications of some of the molecules, especially ALDH1A2, CTSL and ZNF33B at the CC level, deserve to be addressed in future studies.
Synchronization between embryo development and endometrium is a contributing factor for rescue ICSI outcome
Significantly higher clinical pregnancy (29.69% versus 10.81%) and implantation (13.33% versus 5.13%) rates were achieved in group III compared with group II. Therefore, endometrial synchronization is considered a contributing factor for rescue ICSI outcome and embryos derived from rescue ICSI cycles should be cryopreserved and subsequently used in frozen–thawed cycles.
Accumulation of oocytes: a new strategy for managing low-responder patients
The accumulation of oocytes from several ovarian stimulation cycles is currently possible with the aid of novel vitrification technologies. This strategy could be useful for low-responder patients, contributing to increase the inseminated cohort and creating a similar situation as in normal responders.
Simple vitrification for small numbers of human spermatozoa
Techniques for the cryopreservation of small numbers of spermatozoa have attempted to use various types of containers, but these are the only currently available options and the lack of an easily implemented technology has remained a major bottleneck. In the current study, we successfully established a simple cryopreservation method for small numbers of human spermatozoa using the Cell Sleeper, which is a vial type of cell-cryopreservation contai
Sperm gene expression profile is related to pregnancy rate after insemination and is predictive of low fecundity in normozoospermic men
Our findings contribute to the search for the most valuable genetic markers which are potentially useful as tools for predicting pregnancy. Our expression model could complement classical semen analysis in order to identify sperm donors with a less favourable IUI reproductive outcome despite having normal semen parameters.
Relationship quality in lesbian and heterosexual couples undergoing treatment with assisted reproduction
In this study of lesbian and heterosexual couples' relationships, we found that they were generally well adjusted and stable in their relationships when starting treatment with IVF. However, where lesbian women had children from a previous relationship, it decreased relationship quality. For the heterosexual couples previous children did not affect relationship quality.
The effect of GM-CSF on development and aneuploidy in murine blastocysts
GM-CSF exerted a negative impact on blastocyst development at higher concentrations. GM-CSF did not affect the rates of mosaicism/aneuploidy, but did increase the percentage of aneuploid cells within the mosaic embryos.
Genetic Markers to Predict Male Fertility Identified
The diagnosis of male fertility is usually performed through the observation of the sperm in the microscope. However, a normal quality semen does not guarantee an adequate fertility. In fact, there is a considerable proportion of cases of unexplained infertility and data suggest that abnormal sperm function may have a genetic or molecular origin
Fever During Pregnancy More Than Doubles the Risk of Autism or Developmental Delay
A team of UC Davis researchers has found that mothers who had fevers during their pregnancies were more than twice as likely to have a child with autism or developmental delay than were mothers of typically developing children, and that taking medication to treat fever countered its effect.
Weight in Pregnancy Best Controlled by Diet, Study Suggests
Pregnant women, including those who are obese or overweight, should be encouraged to minimise weight gain through diet, according to major new research from Queen Mary, University of London.
It's tough being pregnant: exhaustion and swollen ankles, pregnant women are often overwhelmed with conflicting information on practically everything from eating salad to exercising. We all know exercising is essential for a healthy lifestyle, but many pregnant women feel nervous about physical activity for fear it may harm their unborn child.
The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization.
Cover image of Mol. Hum Reprod 2012 June (select to read more)
The cover shows different types of spermhead defects in proprotein convertase 4 (PCSK4) knockout mice compared with wild-type. Arrowhead acrosin binding protein (ACRBP) positive material, arrow ACRBP negative material.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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