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DISCPLINES: Embryology Andrology Ultrasound Endocrinology
Modules HEB HEC HEE HEF HER HES HET HOva
 
Information on QA Scheme: Blastocyst QAP - 2003
Comment = Images of day 4 and day 5 human embryos for QAP.
Number of enrollments =27 [* This indicates only the number of enrollments. Not all participants will have completed the scheme]
List of QA Issues (or Instalments)
Code Title Available from
HED2003.01-1 Single Human Embryo 1/1/2003
HED2003.01-2 Four human embryos 1/1/2003
HED2003.02-1 Single Human Embryo 1/2/2003
HED2003.02-2 Four human embryos 1/2/2003
HED2003.03-1 Single Human Embryo 1/3/2003
HED2003.04-1 Single Human Embryo 1/4/2003
HED2003.05-1 Single Human Embryo 1/5/2003
HED2003.06-1 Single Human Embryo 1/6/2003
HED2003.07-1 Single Human Embryo 1/7/2003
HED2003.08-1 Single Human Embryo 1/8/2003
HED2003.08-2 Four Mature Embryos 1/8/2003
HED2003.09-1 Single Human Embryo 1/9/2003
HED2003.10-1 Single Human Embryo 1/10/2003
HED2003.11-1 Single Human Embryo 1/11/2003
HED2003.12-1 Single Human Embryo 1/12/2003
List of Questions asked for QA Scheme:Blastocyst QAP - 2003
ID Question Question Format
11 Describe the appearance of the inner cell mass Defined Options
12 Describe the appearance of the trophectoderm Defined Options
9 Describe the degree of compaction. Defined Options
203 Explain why you selected one embryo over the others for transfer? Educational Outcome
95 Grade the embryo on a scale of 0(poor)- 100 (excellent). Numeric Outcome
202 How would you describe this embryo AND GRADE BY YOUR OWN CLINICS GRADING PROCESS? Educational Outcome
35 If the embryo was at the same stage on day 6, would you transfer it ? Defined Options
3 If this was the only embryo availble for freezing, would you freeze it ? Defined Options
28 Is the rate of cleavage normal? Defined Options
7 What degree of variability in Zona Pellucida thickness is evident from the image? Defined Options
210 What is the embryo score for this blastocyst Calculation Outcome
6 What is the thickness of the Zona Pellucida for the nominated culture day? Defined Options
13 What stage of blastocyst formation is evident from the image? Defined Options
27 Which embryo would you rank first? Defined Options
41 Which embryo would you rank fourth? Defined Options
39 Which embryo would you rank second. Defined Options
40 Which embryo would you rank third? Defined Options
1 Would you transfer this embryo if it was the best or only embryo available for transfer? Defined Options
This question has been used in the following computations. - See Calculated Q for more details
Blastocyst Score-Ver 1
Detailed Information on Question: What is the embryo score for this blastocyst
Status This is the KEY QAP Question for the Scheme    
Type Calculation Outcome
Order Question Options
1 The calculated score for this embryo is

Title Blastocyst Score-Ver 1
Comment This score calculates a blastocyst value from the Gardners Grading Scheme
This is a calculated Question. It requires a number of other questions to be completed. The answer to these questions have each been weighted (see below). The value submitted for each question is then compiled as detailed below to provide a SCORE usually out of 100. The higher the score usually indicates a better quality. The score is an arbitary one and has been generated within QAPonline to allow all the parameters embodies in the questions to be assess.
Order Question
Calculation
Summation
1 What stage of blastocyst formation is evident from the image?
Value *4
+
2 Describe the appearance of the inner cell mass
Value *4
+
3 Describe the appearance of the trophectoderm
Value *4
+
4 Is the rate of cleavage normal?
Value *4
+

1 What stage of blastocyst formation is evident from the image?
Order Option
Value
Max value
1 Hatched blastocyst (Gardners Scale 6) [91-100]
10
10
2 Hatching Blastocyst (Gardners Scale 5) [81-90]
9
10
3 Expanded Blastocyst: The blastocoel appears expanded (Gardners Scale 4) [71-80]
8
10
4 Full Blastocyst: The blastocoel is fully developed (Gardners Scale 3) [61-70]
7
10
5 Blastocyst: The blastocoel is more than half the embryo volume (Gardners Scale 2) [51-60]
6
10
6 Early blastocyst: The blastocoel is less than half the embryo volume (Gardners Scale 1) [41-50]
5
10
7 There is no blastocoel evident- fully compacted. [31-40]
4
10
8 Loosley compacted morula [21-30]
3
10
9 Multicellular embryo with early compaction events [11-20]
2
10
10 Arrested, delayed or abnormal development- [1-10]
1
10

2 Describe the appearance of the inner cell mass
Order Option
Value
Max value
1 Inner Cell Mass is tightly packed with many cells (Gardners Scale A)
5
5
2 Inner Cell Mass is loosely packed with several cells (Gardners Scale B)
4
5
3 Inner Cell Mass has very few cells (Gardners Scale C)
3
5
4 The inner cell mass is not visible or not formed.
2
5
5 The inner cell mass is abnormal
1
5

3 Describe the appearance of the trophectoderm
Order Option
Value
Max value
1 Trophectoderm Grade is Good -many cells forming a cohesive epithelium (Gardners Scale A)
5
5
2 Trophectoderm Grade is Average - few cells forming a loose epithelium (Gardners Scale B)
4
5
3 Trophectoderm Grade is Poor - very few large cells(Gardners Scale C)
3
5
4 There is no trophectoderm visible
2
5
5 The trophectoderm is abnormal
1
5

4 Is the rate of cleavage normal?
Order Option
Value
Max value
1 YES, this embryo is normal.
1
1
2 No - this embryo has cleaved or developed faster than expected.
0.75
1
3 No, the embryo is delayed.
0.5
1
4 No, the embryo has arrested or significantly delayed.
0.25
1
5 No, the embryo is abnormal.
0.1
1


 
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