The data indicate that cohesin declines gradually during the long prophase arrest that precedes MI in female mammals. In aged oocytes, cohesin levels fall below the level required to stabilize chiasmata and to hold sister centromeres tightly together
Viewed by:6
-www.cell.com/current-biology/abstract/S0960-9822(1+++++ [Posted on 6/09/2010 1:47:19 AM;894] KW=FertAid Mail/Qanda/Age/Oocytes/
Scientists say they are closer to knowing why older women are more likely to produce abnormal eggs. The Newcastle University team saw a fall in levels of proteins called cohesins, essential for chromosomes to divide properly for fertilisation
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-www.bbc.co.uk/news/health-11164078 +++++ [Posted on 6/09/2010 1:43:41 AM;893] KW=FertAid Mail/Qanda/Age/Oocytes/
Genomic imprinting is an epigenetic phenomenon that is unique to eutherian mammals, marsupials and plants. One characteristic of genomic imprinting is parental origin-specific expression of imprinted genes.
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-molehr.oxfordjournals.org/cgi/content/abstract/16/+++++ [Posted on 1/09/2010 9:04:11 AM;892] KW=FertAid Mail/Qanda/Imprinting/Epigenetics/Risks/
There is substantial interobserver variability and moderate intraobserver variability among embryologists. Such variability could alter both the expected quality of embryos transferred, as well as the number transferred, both of which directly impact
Viewed by:7
-www.fertstert.org/article/S0015-0282(06)03047-0/fu+++++ [Posted on 31/08/2010 8:00:14 AM;890] KW=FertAid/kappa/Grading/
Among 12 investigated possible predictive factors in standard patients, the total number of antral follicles and ovarian stromal blood flow assessed by total Power Doppler score are the two most significant predictors of ovarian response. Suggestion
Thus, a spontaneous cycle and the GnRH antagonist Cetrorelix in single dose administration could represent a first-choice IVF treatment with none of the complications and risks of current controlled ovarian hyperstimulation protocols, and an acceptab
Viewed by:7
-humrep.oxfordjournals.org/cgi/content/full/14/3/68+++++ [Posted on 31/08/2010 1:18:34 AM;888] KW=FertAid Mail/Qanda/Natural Cycles/
Evidence in favour of mild ovarian stimulation for IVF is accumulating in recent literature. However, further, sufficiently powered prospective studies applying novel mild treatment regimens are required and structured reporting of the incidence and
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-humupd.oxfordjournals.org/cgi/content/full/15/1/13+++++ [Posted on 31/08/2010 1:10:11 AM;887] KW=FertAid Mail/Qanda/Minimal Stimulation/FSH Dose/
Use of the CONSORT algorithm achieved an adequate oocyte yield and good pregnancy rates in this preliminary study. Adjustment of the algorithm could reduce cancellation rates.
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-www.rbmojournal.com/article/S1472-6483(10)60256-8/+++++ [Posted on 31/08/2010 12:53:30 AM;885] KW=FertAid Mail/Qanda/Minimal Stimulation/CONSORT/FSH dose/
Cleavage embryos arising from ICSI cycles using testicular and epididymal spermatozoa can be frozen with survival, pregnancy, and implantation rates comparable to those obtained with ejaculated spermatozoa.
Viewed by:7
-www.fertstert.org/article/S0015-0282(07)04341-5/ab+++++ [Posted on 29/08/2010 12:49:43 PM;884] KW=FertAid Mail/Qanda/Surgical Sperm/TESA/MESA/PESA/
Oocyte yield may be considered as an indicator of ovarian response to hormone stimulation. In women up to 40 years a high yield of oocytes after superovulation is associated with an increased chromosome error rate.
Viewed by:7
-www.fertstert.org/article/S0015-0282(08)00016-2/ab+++++ [Posted on 29/08/2010 12:39:13 PM;883] KW=FertAid Mail/Qanda/Egg number/Mitotic Error/Recruitment/
In addition, it is now a requirement of laboratory accreditation systems that laboratories provide clinical validation for all methods used (ie, demonstrate that they are
Viewed by:6
-www.andrologyjournal.org/cgi/content/full/28/3/364+++++ [Posted on 27/08/2010 4:40:14 PM;882] KW=Andrology/Concentration/Counting/ Makler/
Overweight women undergoing fertility treatment have double the risk of miscarriage of normal weight women, a UK study says. More than a third of overweight and obese women had a miscarriage compared with one in five of normal weight women, a fertil
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-www.bbc.co.uk/news/10434138 +++++ [Posted on 27/08/2010 12:56:47 AM;881] KW=FertAid Mail/Qanda/Obesity/Overweight/Success/
In this way, the study of the cumulus cells (CCs) transcriptomic profile offers the opportunity, by a non-invasive method, to predict oocyte and embryo competence because bidirectional traffic between CCs and the oocyte is very important for the acqu
Viewed by:22
-molehr.oxfordjournals.org/cgi/content/abstract/16/+++++ [Posted on 21/08/2010 2:09:43 PM;879] KW=FertAid Mail/Qanda/cumulus cells/microarrays/pregnancy/non-invasive biomarkers/embryo
This is the first prospective, randomized, blinded and paired comparison between microarray and FISH-based aneuploidy screening. SNP microarray-based 24 chromosome aneuploidy screening provides more complete and consistent results than FISH. These re
The possibility that different transcript levels in the oocyte have an impact on cellular pathways remains to be proven. However, it may be significant that some of the highlighted genes produce proteins involved in spindle assembly and chromosome al
Gender significantly (P < 0.05) affected the metabolism of tryptophan, leucine and asparagine by cleavage-stage embryos. Pronucleate zygotes had a significantly higher proportion of active:inactive mitochondria compared with cleavage-stage embryos. F
Viewed by:15
-molehr.oxfordjournals.org/cgi/content/abstract/16/+++++ [Posted on 21/08/2010 1:49:08 PM;876] KW=FertAid/Qanda/aneuploidy/mitochondria/metabolomics/embryo development/FISH