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What to do when good-quality embryos repeatedly fail to implant
...Consideration should be given to preimplantation genetic screening (PGS) and the adoption of a “freeze-all” protocol. Treatment offered should be evidence based, aimed at improving embryo quality or endometrial receptivity. Gamete donation or surrogacy may be necessary if there is no realistic chance of success with further IVF attempts.
The increasing levels of IL-1β: over time are consistent with the known role of the IL-1 cytokine family in implantation and pregnancy. Additionally, we confirm in a prospective investigation the positive relationship between detectable serum IL-1β: at the start of IVF cycle and outcome.
Mammalian sperm contain two factors for calcium release and egg activation: Phospholipase C zeta and a cryptic activating factor
Mammalian sperm induce a series of calcium oscillations in the egg at fertilization responsible for triggering the transition to a 1-cell embryo and for blocking polyspermy. Phospholipase C (PLC) zeta is a sperm-specific protein capable of mimicking these fertilization calcium changes through its ability to generate inositol trisphosphate. Here I comment on two recent landmark studies that report on knockout of PLC zeta in mice.
Undetectable Serum Levels of Anti-Müllerian Hormone in Women with Ovarian Hyperstimulation Syndrome During In Vitro Fertilization and Successful Pregn
We report a unique case of undetectable serum levels of anti-müllerian hormone (AMH) in women with polycystic ovary syndrome (PCOS) who developed ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF). A case is described of a 28-year-old woman with clinical symptoms of PCOS and AMH serum level below analytical sensitivity (<1.0 pmol/L).
Effects of Conception Using Assisted Reproductive Technologies on Infant Health and Development: An Evolutionary Perspective and Analysis Using UK Mil
This suggests that evolved processes that determine which egg and sperm lead to successful pregnancy may be important for offspring quality as indicated by infant development. Clinically, the results suggest that women should avoid ART with artificial gamete selection if they can conceive using other ART methods.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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