Comment:A collection of articles on environmental factors including the effect of PBC in follicular fluid and IVF, trace elements on sperm DNA Fragmentation and on embryo development and pregnancy. A paper looking at paraffin and mineral oil and embryo culture is reassuring while Prof Winston's new item on social egg freezing.
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Evaluation of trace metals in follicular fluid in ICSI-treated patients
The dependent variable was the fact of achieving pregnancy, and the independent variable tested was the level of trace metals. Ultimately, only one variable remained statistically significant in the model: the level of Se.....Analysis of the effects of the average concentrations of Se, Zn, and Cu on the developmental dynamics of embryos showed that higher concentrations of these metals were accompanied by shorter lead times for each of the variou
Evaluation of effect of selected trace elements on dynamics of sperm DNA fragmentation.
The levels of lead and cadmium were higher in seminal plasma of infertile men, compared to fertile men. The levels of zinc, copper and selenium in seminal plasma were higher in men with proven fertility, compared to infertile men, and did not exert a significant effect on the dynamics of sperm DNA fragmentation. The level of cadmium had no significant effect on intensification of sperm DNA fragmentation in time.Reports in the literature which con
The effect of follicullar fluid pesticides and polychlorinated biphenyls concentrations on intracytoplasmic sperm injection (ICSI) embryological and c
Higher concentrations of any studied PCBs and pesticides are associated with thinner endometrial thickness. The higher the level of Pretilachlor, β:-cyfluthrin, PCB 28 and 180, the lower the retrieval, fertilization, and embryo cleavage rates. High PCB and pesticide concentrations in the FF adversely affected embryological ICSI outcomes. However, more data are needed to evaluate their effect on the clinical outcome.
Comparison between paraffin and mineral oil covering on early human embryo culture: a prospective randomized study
Despite the different characteristics of these two oils regarding hydrocarbon saturation, packing and temperature storage, Ovoil™ and LiteOil® can be used in parallel in the same IVF protocol.
Robert Winston’s warning against ‘greedy fertility clinics’
Read more: https://metro.co.uk/2018/08/17/robert-winstons-warning-against-greedy-fert
Fertility expert Robert Winston has cautioned women against freezing their eggs claiming they are at risk of being exploited by the ‘greed’ of private clinics. The leading professor said women were being misled by inaccurate statistics and could be wasting money in their desperate hope to one day have a child. His warning comes just days after the Royal College of Obstetricians and Gynaecologists said women needed to be made more aware of just ho
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There were significant negative correlations between FF concentrations of the eight examined pesticides and the four PCBs on the endometrial thickness.
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Pretilachlor, chlorpyrifos, beta-cyfluthrin, and Diazinon were the only toxic agents that negatively correlated with the number of the oocytes retrieved.
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high concentrations of Lindane,DDT, Diazinon,and chlorpyrifos were significantly associated lower implantation rate
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PCB 28 and 180 concentration in the FF was associated with a lower number of retrieved oocytes and fertilization rate, respectively
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The number of implanted embryos was negatively correlated with PCB 52 FF concentration.
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the clinical pregnancy rate reached the level of significance.
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