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pH: the silent variable significantly impacting meiotic spindle assembly in mouse oocytes
Conclusions: This study has shown that the meiotic spindle in mouse oocytes is highly sensitive to changes in oocyte culture media pH. If comparable in humans, this has significance as to the pH level of culture media currently used in assisted reproductive technology clinics worldwide, and reinforces the requirement for stringent control over extrinsic variables in the IVF laboratory.
pH stability of human preimplantation embryo culture media: effects of culture and batches
Conclusions: A relevant difference in pH was found between batches of human preimplantation embryo culture media. This suggests that the CO2 level of incubators may need to be adjusted for new batches of culture medium based on measured pH, to anticipate batch variability and safely accommodate limited pH increase over time. This study was unable to identify the cause of the differences in pH between batches, and further investigation on a larger
We hope that you enjoy reading this monograph as much as we enjoyed making it, and that wherever you are in the arc of reproductive medical history, it will give you insights into the remarkable field that gives birth to the unborn.
Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition [in mice]
Together, our study for the first time demonstrates that maternal HFD insult causes sustained alterations of the mesolimbic dopaminergic system suggestive of a predisposition to develop obesity and addictive-like behaviors across multiple generations.
Mice eat too much food if their great grandmother did the same [New Scientist-News in Brief]
IF A female mouse has a fatty diet just before, during and just after pregnancy, her pups, grandpups and great-grandpups have a raised risk of obesity and addiction. Animal studies have shown that such a high-fat diet can lead to offspring with a less sensitive reward system: they need more food to feel full and are more susceptible to becoming obese or addicted to drugs.
In-line filter for cylinder and house gasses
O2, N2, CO2, and tri-gas. Aire~LifeLine provides in-line air filtration with top of the line protection, delivering a better and more consistent yield of cylinder and house gasses for a wide range of med
Vit Kit - Warm NX is an adaptable, cost-effective system for use in the thawing of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Unlike many vitrification kits that feature a mono-buffered system and M199 base med
Vit Kit - Freeze NX is an adaptable, cost-effective system for use in the vitrification of oocytes, pronuclear zygotes, cleavage stage embryos, and blastocyst stage embryos. Vit Kit - Freeze NX is the latest advancement in vitrification media aimed t
S-Cryolock is the slimmer version of the original. It is a versatile, simple and efficient vitrification device that is intended for the holding, cryopreservation and storage of oocytes or embryos in liquid nitrogen.
Source
Irvine Scientific
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